CAS 1071992-57-8

Xevinapant hydrochloride

CAS : 1071992-57-8

Xevinapant hydrochloride (AT-406 HCl) , an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide.

Formule : C₃₂H₄₄ClN₅O₄

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 598.19

Ref: TM-T3299

AT-406 hydrochloride

CAS : 1071992-57-8

AT-406 hydrochloride is an analog of the anticancer protein kinase inhibitor, SMAC. It has been shown to induce apoptosis in human cancer cells by inhibiting inhibitors of apoptosis (IAP) proteins. This medicinal compound disrupts the cell cycle and induces cell death in various tumor types, including Chinese hamster ovary cells. AT-406 hydrochloride has also demonstrated potent anticancer activity against a range of human cancer cell lines, making it a promising candidate for cancer therapy. Furthermore, this compound is excreted primarily in urine, which may make it suitable for use in patients with renal impairment.

Formule : C₃₂H₄₃N₅O₄

Degré de pureté : Min. 95%

Masse moléculaire : 561.7 g/mol

Ref: 3D-WSB99257