CAS 108060-84-0

O6-Benzyl-N2,3-etheno guanosine

CAS : 108060-84-0

Ref: 7W-GC3023

O6-Benzyl-N2,3-etheno Guanosine-13C2,d

Produit contrôlé

CAS : 108060-84-0

Applications Intermediate in the preparation of labelled, fluorescent Guanosine nucleotide analogs.

Formule : C₂C₁₇DH₁₈N₅O₅

Couleur et forme : Neat

Masse moléculaire : 400.376

Ref: TR-B276492

O6-Benzyl-N2,3-etheno guanosine

CAS : 108060-84-0

O6-Benzyl-N2,3-etheno guanosine is a phosphoramidite that can be used in the synthesis of DNA. It is a novel nucleoside analog with antiviral and anticancer properties. O6-Benzyl-N2,3-etheno guanosine has been shown to increase the antitumor activity of cisplatin in vitro and in vivo, as well as its ability to inhibit human immunodeficiency virus type 1 (HIV-1) replication. This compound also inhibits the replication of herpes simplex virus type 2 (HSV-2) without affecting the expression of cellular proteins. O6-Benzylguanosine is synthesized by reacting N2,3-ethenoguanosine with benzaldehyde in dichloromethane under microwave irradiation.

Formule : C₁₉H₁₉N₅O₅

Degré de pureté : Min. 95%

Masse moléculaire : 397.38 g/mol

Ref: 3D-NB16629