CAS 112242-17-8

Buprenorphine N-Oxide

Produit contrôlé

CAS : 112242-17-8

Formule : C₂₉H₄₁NO₅

Couleur et forme : Neat

Masse moléculaire : 483.64

Ref: 86-MM0120.15

Buprenorphine N-oxide

Produit contrôlé

CAS : 112242-17-8

Applications Prodrug of Buprenorphine, exhibits improved bioavailability

Formule : C₂₉H₄₁NO₅

Couleur et forme : Yellow

Masse moléculaire : 483.64

Ref: TR-B689575

Buprenorphine N-oxide (1 mg/ml in Methanol)

Produit contrôlé

CAS : 112242-17-8

Formule : C₂₉H₄₁NO₅

Couleur et forme : Single Solution

Masse moléculaire : 483.64

Ref: TR-KIT9785

Buprenorphine N-oxide - 1.0mg/ml in Acetonitrile

Produit contrôlé

CAS : 112242-17-8

Buprenorphine N-oxide is a metabolite of buprenorphine. It is the major component in human urine, with a concentration of 0.2% to 2%. The elimination of buprenorphine N-oxide has been shown to be slower than that of buprenorphine in humans. Buprenorphine N-oxide is an active metabolite that binds to the same opioid receptors as buprenorphine and norbuprenorphine. This drug has been shown to have similar effects on the human liver as buprenorphine, but it does not cause respiratory depression or sedation. Buprenorphine N-oxide also has been shown to inhibit cytochrome P450 enzymes in the liver microsomes of rats and mice, which may lead to an increase in the rate of elimination of other drugs, such as methadone and propoxyphene, by competing for hepatic metabolism.

Formule : C₂₉H₄₁NO₅

Degré de pureté : Min. 95%

Couleur et forme : Powder

Masse moléculaire : 483.64 g/mol

Ref: 3D-FB19362