CAS 1129403-56-0

BBI-503(BB-503)

CAS : 1129403-56-0

Formule : C₃₁H₃₃N₅O₂S

Degré de pureté : 99%

Couleur et forme : Solid

Masse moléculaire : 539.6910

Ref: IN-DA008TOW

Amcasertib

CAS : 1129403-56-0

Amcasertib

Degré de pureté : ≥95%

Masse moléculaire : 539.69g/mol

Ref: 54-BUP12916

Amcasertib

CAS : 1129403-56-0

Amcasertib (BBI503) is an orally administered investigational agent designed to inhibit cancer stem cell pathways via targeting stemness kinases.

Formule : C₃₁H₃₃N₅O₂S

Degré de pureté : 97.56% - >99.99%

Couleur et forme : Solid

Masse moléculaire : 539.69

Ref: TM-T3995

Amcasertib

Produit contrôlé

CAS : 1129403-56-0

Formule : C₃₁H₃₃N₅O₂S

Couleur et forme : Neat

Masse moléculaire : 539.691

Ref: TR-A634611

Amcasertib (BBI503)

CAS : 1129403-56-0

Amcasertib is a β-catenin inhibitor that inhibits tumor growth and metastasis. It is currently in clinical trials for the treatment of cancer. Amcasertib inhibits the phosphorylation of β-catenin by GSK3β, which leads to its degradation by proteasomes, thereby reducing cellular levels of β-catenin. Amcasertib has also been shown to enhance the cytotoxicity of folfirinox, an anticancer drug. Amcasertib has a hydroxyl group at C-2 and a carbonyl group at C-4, which are necessary for binding to β-catenin. The lack of a disulfide bond makes amcasertib more stable than other potential β-catenin inhibitors.

Formule : C₃₁H₃₃N₅O₂S

Degré de pureté : Min. 95%

Masse moléculaire : 539.69 g/mol

Ref: 3D-EVB40356