CAS 114-25-0

Biliverdine

Description :

Biliverdine est un pigment biliaire tétrapyrrolique vert qui est un produit de la dégradation de l'hème, formé principalement à partir de la décomposition de l'hémoglobine. Il se caractérise par sa couleur verte, qui est due à son système de doubles liaisons conjuguées, lui permettant d'absorber la lumière dans le spectre visible. Biliverdine est soluble dans l'eau et a une formule moléculaire de C33H34N4O6, avec un poids moléculaire d'environ 582,6 g/mol. Il joue un rôle significatif dans divers processus biologiques, y compris en agissant comme un antioxydant et en participant à la régulation des fonctions cellulaires. Biliverdine est également un précurseur de la bilirubine, un autre pigment biliaire important. En termes de stabilité, Biliverdine peut être sensible à la lumière et aux changements de pH, ce qui peut affecter sa structure et sa réactivité. Sa présence dans les systèmes biologiques est souvent associée à la fonction hépatique et peut être indicative de certaines conditions médicales lorsqu'elle est trouvée en concentrations anormales. Dans l'ensemble, Biliverdine est un composé important en biochimie et en médecine, reflétant les processus complexes du métabolisme de l'hème.

Formule : C₃₃H₃₄N₄O₆

InChI : InChI=1/C33H34N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-15,35H,1-2,9-12H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-,28-15-

Code InChI : InChIKey=QBUVFDKTZJNUPP-BBROENKCSA-N

SMILES : C(\C1=C(CCC(O)=O)C(C)=C(/C=C\2/C(C=C)=C(C)C(=O)N2)N1)=C3/C(CCC(O)=O)=C(C)C(/C=C\4/C(C)=C(C=C)C(=O)N4)=N3

Synonymes :

• 21H-Biline-8,12-dipropanoic acid, 3,18-diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-
• 3,18-Diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid
• 3-[(2Z)-2-[[3-(2-carboxyethyl)-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-2-yl]methylene]-4-methyl-5-[(Z)-(3-methyl-5-oxo-4-vinyl-pyrrol-2-ylidene)methyl]pyrrol-3-yl]propanoic acid
• 3-[2-[(E)-[(5E)-3-(2-carboxyethyl)-4-methyl-5-[(3-methyl-5-oxo-4-vinyl-pyrrol-2-yl)methylene]pyrrol-2-ylidene]methyl]-4-methyl-5-[(E)-(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
• 3-[2-[(Z)-[(5E)-3-(2-carboxyethyl)-4-methyl-5-[(3-methyl-5-oxo-4-vinyl-pyrrol-2-yl)methylene]pyrrol-2-ylidene]methyl]-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
• 3-[2-[(Z)-[(5Z)-3-(2-carboxyethyl)-4-methyl-5-[(3-methyl-5-oxo-4-vinyl-pyrrol-2-yl)methylene]pyrrol-2-ylidene]methyl]-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
• 3-[2-[[3-(2-carboxyethyl)-4-methyl-5-[(3-methyl-5-oxo-4-vinyl-pyrrol-2-yl)methylene]pyrrol-2-ylidene]methyl]-4-methyl-5-[(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
• Biline-8,12-dipropionic acid, 1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-
• Biline-8,12-dipropionic acid, 1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl- (8CI)
• Biliverdin IXalpha
• Biliverdin IXα
• Biliverdina
• Biliverdine
• Biliverdine (VAN)
• Biliverdine dihydrochloride
• Dehydrobilirubin
• Nsc 62793
• Oocyan
• Protobiliverdin IXα
• Pyrrole-3-propionic acid, 2-[[3-(2-carboxyethyl)-4-methyl-5-[(3-methyl-5-oxo-4-vinyl-3-pyrrolin-2-ylidene)methyl]-2H-pyrrol-2-ylidene]methyl]-4-methyl-5-[(4-methyl-5-oxo-3-vinyl-3-pyrrolin-2-ylidene)methyl]-
• Uteroverdine
• α-Biliverdin
• Biliverdin
• 3-[2-[(Z)-[(5E)-3-(2-carboxyethyl)-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-yl)methylidene]-4-methyl-pyrrol-2-ylidene]methyl]-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
• 3-[2-[(E)-[(5E)-3-(2-carboxyethyl)-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-yl)methylidene]-4-methyl-pyrrol-2-ylidene]methyl]-5-[(E)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
• ocyan
• 3,18-Diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetrametyl-1,19-dioxo-21H-biline-8,12-dipropanoic Acid

3,18-Diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid

CAS : 114-25-0

Formule : C₃₃H₃₄N₄O₆

Degré de pureté : 70%

Couleur et forme : Solid

Masse moléculaire : 582.6463

Ref: IN-DA0038B8

Biliverdine

CAS : 114-25-0

Stability Light Sensitive
Applications Biliverdine is a precursor of Bilirubin. Biliverdine is formed in the body from hemoglobin. The bile of amphibians and of birds contains Biliverdine only. It is also an inhibitor for hepatitis C virus.
References Lemberg et al.: Biochem. J., 35, 363 (1941); Gutierrez-Grobe, Y. et al.: Annals. Hepatol., 10, 105 (2011);

Formule : C₃₃H₃₄N₄O₆

Couleur et forme : Dark Green To Black

Masse moléculaire : 582.65

Ref: TR-B386400

Biliverdine-d4 (Major, may contain up to 3% d0) (Technical Grade)

Produit contrôlé

CAS : 114-25-0

Applications Labelled Biliverdine is a precursor of Bilirubin. Biliverdine is formed in the body from hemoglobin. The bile of amphibians and of birds contains Biliverdine only. It is also an inhibitor for hepatitis C virus.
References Lemberg et al.: Biochem. J., 35, 363 (1941); Gutierrez-Grobe, Y. et al.: Annals. Hepatol., 10, 105 (2011);

Formule : C₃₃H₃₀D₄N₄O₆

Degré de pureté : >90%

Couleur et forme : Neat

Masse moléculaire : 586.67

Ref: TR-B386402

Biliverdine

CAS : 114-25-0

Biliverdine is a fluorescent probe that selectively binds to bilirubin and other hydroxycinnamic acids in tissue. Biliverdine can be used to measure the oxidative injury of tissues as well as the activity of enzymes involved in the metabolism of these compounds. The use of biliverdin with other fluorescent probes has been shown to improve the sensitivity and specificity for detecting oxidative injury. Biliverdin has also been shown to have anti-inflammatory properties, which may be due to its ability to inhibit the production of growth factor-β1 and 4-hydroxycinnamic acid.

Formule : C₃₃H₃₄N₄O₆

Degré de pureté : Min. 70 Area-%

Couleur et forme : Green Powder

Masse moléculaire : 582.65 g/mol

Ref: 3D-FB18596

Biliverdin

CAS : 114-25-0

Biliverdin, produced through the oxidation of bilirubin, can also be synthesized through a non-protoporphyrin pathway in Corynebacterium glutamicum [1].

Formule : C₃₃H₃₄N₄O₆

Couleur et forme : Solid

Masse moléculaire : 582.65

Ref: TM-T84736