CAS 1148113-53-4

Aprepitant Related Compound A (3-[[(2R,3R)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholino]methyl]-1H-1,2,4-triazol-5(4H)-one)

CAS : 1148113-53-4

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formule : C₂₃H₂₁F₇N₄O₃

Couleur et forme : White Off-White Powder

Masse moléculaire : 534.15019

Ref: 45-1041915

(R,R,R)-Aprepitant

CAS : 1148113-53-4

Formule : C₂₃H₂₁F₇N₄O₃

Degré de pureté : 95%

Couleur et forme : Solid

Masse moléculaire : 534.4267

Ref: IN-DA008XK3

Aprepitant USP Related Compound A ((1R,2R,3R)-Aprepitant)

CAS : 1148113-53-4

Formule : C₂₃H₂₁F₇N₄O₃

Couleur et forme : White To Off-White Solid

Masse moléculaire : 534.43

Ref: 4Z-A-324

3-[[(2R,3R)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholino]methyl]-1H-1,2,4-triazol-5(4H)-one ((R,R,R)-Aprepitant)

Produit contrôlé

CAS : 1148113-53-4

Formule : C₂₃H₂₁F₇N₄O₃

Couleur et forme : Neat

Masse moléculaire : 534.43

Ref: 86-MM3251.01

Aprepitant USP Related Compound A

CAS : 1148113-53-4

Formule : C₂₃H₂₁F₇N₄O₃

Masse moléculaire : 534.43

Ref: ST-EA-CP-A109028

(R,R,R)-Aprepitant

CAS : 1148113-53-4

Aprepitant is a neurokinin-1 receptor antagonist. It is an antiemetic which suppresses nausea and vomiting and has proven to be especially useful alongside cancer chemotherapy and as a tool in cancer-related studies. Aprepitant binds to the neurokinin-1 receptor in the brain, preventing it from binding to substance P. This prevents substance P from stimulating nerves in the vomiting center of the brain, reducing feelings of nausea and vomiting. Aprepitant has been shown to be effective against HIV infection, with no major side effects. The use of aprepitant for HIV therapy may be limited due to its ability to cause serious liver damage when taken with other drugs that are metabolized by cytochrome P450 enzymes.

Formule : C₂₃H₂₁F₇N₄O₃

Degré de pureté : Min. 95%

Masse moléculaire : 534.43 g/mol

Ref: 3D-FA17961