CAS 1154097-71-8
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8 produits concernés.
IOX-4
CAS :Formule :C15H16N6O3Degré de pureté :>95.0%(HPLC)(qNMR)Couleur et forme :Light yellow to Amber powder to crystalMasse moléculaire :328.33IOX4
CAS :IOX4 is a potent PHD2 inhibitor (IC50 = 1.6 nM)Formule :C15H16N6O3Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :328.33IOX4
CAS :Produit contrôlé<p>Applications IOX4 is a triazole based potent and selective inhibitor of hypoxia-inducible factor (HIF) prolyl-hydroxylase. It induces HIFα in cells of mouse brain. It is useful for studies that aim to validate the upregulation of HIF for treatment of cerebral diseases such as stroke.<br>References Chan, M., et al.: PLOS ONE, 10, e0132004/1 (2015);<br></p>Formule :C15H16N6O3Couleur et forme :NeatMasse moléculaire :328.33IOX4
CAS :<p>IOX4 is a benzodiazepine receptor antagonist that blocks the binding of benzodiazepines to their receptors in the central nervous system. This leads to an increase in oxygen transport and improved cancer treatment. IOX4 has been shown to inhibit the activity of G-protein coupled receptor kinase 2 (GRK2) and phospholipase C (PLC). These two proteins are critical for signal transduction, which may play a role in cancer development. IOX4 is currently being studied as a backup drug for benzodiazepine receptor antagonists with inhibitory effects on GRK2 and PLC.</p>Formule :C15H7D9N6O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :337.38 g/mol
