
CAS 1159408-65-7
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5 produits concernés.
Tri-GalNAc(OAc)3 TFA
CAS :Formule :C81H129F3N10O38Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1907.9304Tri-GalNAc(OAc)3 (TFA)
CAS :Tri-GalNAc(OAc)3 (TFA)Degré de pureté :98%Masse moléculaire :1907.93g/molTri-GalNAc(OAc)3 TFA
CAS :Tri-GalNAc(OAc)3 TFA, a triantenerrary N-acetylgalactosamine (tri-GalNAc) ligand, is utilized in the synthesis of GalNAc-lysosome-targeting chimera (GalNAc-Formule :C81H129F3N10O38Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1907.93Tri-b-GalNAcAc3-amine TFA
CAS :<p>Tri-b-GalNAc-amine formate salt is an ASGPR-targeted ligand for therapeutics and diagnostics. With three terminal beta-GalNAc (N-acetylgalactosamine) sugars in a trivalent configuration, its high-affinity permits binding to the asialoglycoprotein receptor (ASGPR) on hepatocytes. Notably, the presence of a protonated primary amine group allows for chemoselective bioconjugation with various functional moieties via established amide bond formation techniques. Its salt form (TFA salt) enhances the water solubility of the molecule, facilitating its use in aqueous reaction buffers commonly employed in bioconjugation protocols. This combination of specific ASGPR targeting and a readily available conjugation site makes tri-b-GalNAc-amine TFA a valuable tool for developing customized and targeted drug-GalNAc conjugates, siRNA delivery vehicles, or ASGPR-specific probes. The use of TFA as a counterion ensures efficient deprotonation of the amine during conjugation, potentially improving reaction efficiency.</p>Formule :C79H128N10O36C2HF3O2Degré de pureté :Min. 95 Area-%Masse moléculaire :1,907.93 g/mol





