CAS 1193383-09-3

1H-Pyrazole-4-carboxylic acid, 1-[6-chloro-5-(trifluoromethoxy)-1H-benzimidazol-2-yl]-

CAS : 1193383-09-3

Formule : C₁₂H₆ClF₃N₄O₃

Degré de pureté : %

Couleur et forme : Solid

Masse moléculaire : 346.6492

Ref: IN-DA000IM5

1-(6-Chloro-5-(Trifluoromethoxy)-1H-Benzo[D]Imidazol-2-Yl)-1H-Pyrazole-4-Carboxylic Acid

CAS : 1193383-09-3

1-(6-Chloro-5-(Trifluoromethoxy)-1H-Benzo[D]Imidazol-2-Yl)-1H-Pyrazole-4-Carboxylic Acid

Degré de pureté : 98+%

Masse moléculaire : 346.65g/mol

Ref: 54-PC108738

JNJ-42041935

CAS : 1193383-09-3

JNJ-42041935

Degré de pureté : ≥95%

Masse moléculaire : 346.65g/mol

Ref: 54-BUP08199

JNJ-42041935

CAS : 1193383-09-3

JNJ-42041935 (HIF-PHD Inhibitor II) is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.

Formule : C₁₂H₆ClF₃N₄O₃

Degré de pureté : 99.58% - ≥95%

Couleur et forme : Solid

Masse moléculaire : 346.65

Ref: TM-T3180

JNJ 42041935

Produit contrôlé

CAS : 1193383-09-3

Applications JNJ 42041935 is a selective hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) enzyme inhibitor. It can potentially be used for the treatment of inflammation-induced anemia.
References Barrett, T., et al.: Mol. Pharmacol., 79, 910 (2011); Thirstrup, K., et al.: Pharmacol. Res., 64, 268 (2011);

Formule : C₁₂H₆ClF₃N₄O₃

Couleur et forme : Neat

Masse moléculaire : 346.65

Ref: TR-J211318

JNJ 42041935

CAS : 1193383-09-3

JNJ 42041935 is a pharmacologic agent that inhibits the growth of cancer cells and may be used to treat chronic kidney disease. This drug binds to the extracellular matrix, which prevents the proliferation of cells in the tissue. JNJ 42041935 has been shown to inhibit the production of messenger RNA in urine samples taken from patients with chronic kidney disease. The clinical studies have shown that JNJ 42041935 can reduce the incidence of leukemia and blood disorders. The effective dose for this drug is not yet known, but it is thought that it may be around 1-10 mg/kg daily. It is also unknown how long JNJ 42041935 will remain in the body or what its excretion rate is.

Formule : C₁₂H₆ClF₃N₄O₃

Degré de pureté : Min. 95%

Masse moléculaire : 346.65 g/mol

Ref: 3D-TXB38309