CAS 1198221-21-4

TAS-114

CAS : 1198221-21-4

TAS-114 is an investigational drug characterized as a novel oral inhibitor. It is derived from the synthetic modification of existing compounds to enhance bioavailability and efficacy. The mechanism of action for TAS-114 involves dual inhibition of the enzyme dihydropyrimidine dehydrogenase (DPD) and base excision repair pathways, which are responsible for degrading pyrimidine analogs and repairing DNA, respectively. By inhibiting these pathways, TAS-114 enhances the efficacy of fluoropyrimidines, a class of chemotherapeutic agents, by preventing their catabolism and improving DNA damage persistence.

Formule : C₂₁H₂₉N₃O₆S

Degré de pureté : Min. 95%

Masse moléculaire : 451.5 g/mol

Ref: 3D-YXB22121

TAS-114

CAS : 1198221-21-4

TAS-114 is a dUTPase and DPD inhibitor that modulates catabolic pathways to improve systemic availability of 5-FU.

Formule : C₂₁H₂₉N₃O₆S

Degré de pureté : 99.76%

Couleur et forme : Solid

Masse moléculaire : 451.54

Ref: TM-T13089