CAS 1212650-12-8

8-Bromo-9-(b-D-xylofuranosyl)guanine

CAS : 1212650-12-8

8-Bromo-9-(b-D-xylofuranosyl)guanine is a Nucleoside Derivative - Xylo-nucleoside; 8-Modified purine nucleoside.

Formule : C₁₀H₁₂BrN₅O₅

Couleur et forme : Solid

Masse moléculaire : 362.14

Ref: TM-TNU0382

8-Bromo-9-(b-D-xylofuranosyl)guanine

CAS : 1212650-12-8

8-Bromo-9-(beta-D-xylofuranosyl)guanine (8BrG) is a modified nucleoside that has been shown to inhibit DNA and RNA synthesis in cells. This compound is also an antiviral agent with activity against herpes simplex virus type 1, herpes simplex virus type 2, and HIV. 8BrG inhibits the production of viral diphosphate and ribonucleosides by competitive inhibition of cellular enzymes involved in nucleotide biosynthesis. 8BrG is not active against bacterial cells, which lack these enzymes. 8BrG is synthesized by the addition of a bromine to the 9th position of guanine. It is a novel nucleotide that may have applications as an activator for other drugs or as a cancer treatment.

Formule : C₁₀H₁₂BrN₅O₅

Degré de pureté : Min. 95%

Masse moléculaire : 362.14 g/mol

Ref: 3D-NB163092