CAS 1215010-55-1

DDD85646

CAS : 1215010-55-1

DDD85646

Degré de pureté : ≥95%

Masse moléculaire : 495.43g/mol

Ref: 54-BUP03515

DDD85646

Produit contrôlé

CAS : 1215010-55-1

Applications DDD85646 is a potent inhibitor of Trypanosoma brucei N-myristoyltransferase (TbNMT).
References Brand, Stephen., et al.: J. Med. Chem, 57, 9855 (2014);

Formule : C₂₁H₂₄Cl₂N₆O₂S

Couleur et forme : Neat

Masse moléculaire : 495.425

Ref: TR-D195323

DDD85646

CAS : 1215010-55-1

DDD85646 is a potent inhibitor of leishmania. It binds to the active site of protein synthesis by blocking the aminoacyl-tRNA binding site. DDD85646 has been shown to have a significant interaction with chemotherapeutic drugs, including doxorubicin and vincristine. This molecule may be a potential drug target for the treatment of cancer and infectious diseases. DDD85646 also inhibits fatty acid synthesis, which may lead to weight loss.

Formule : C₂₁H₂₄Cl₂N₆O₂S

Degré de pureté : Min. 95%

Masse moléculaire : 495.4 g/mol

Ref: 3D-QYB01055

DDD85646

CAS : 1215010-55-1

DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.

Formule : C₂₁H₂₄Cl₂N₆O₂S

Degré de pureté : 97.8% - 99.76%

Couleur et forme : Solid

Masse moléculaire : 495.43

Ref: TM-T27135