CAS 1217623-74-9

4(3H)-Quinazolinone, 7-bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-, hydrochloride (1:1), rel-

CAS : 1217623-74-9

Formule : C₁₆H₁₈BrCl₂N₃O₃

Couleur et forme : Solid

Masse moléculaire : 451.1424

Ref: IN-DA0015U8

Halofuginone HCl

CAS : 1217623-74-9

Formule : C₁₆H₁₇BrClN₃O₃·HCl

Masse moléculaire : 414.68 36.46

Ref: 4Z-H-035002

Halofuginone Hydrochloride

Produit contrôlé

CAS : 1217623-74-9

Formule : C₁₆H₁₇BrClN₃O₃·ClH

Couleur et forme : Colourless Solid

Masse moléculaire : 451.14

Ref: TR-H102500

Halofuginone-13C,15N2 Hydrochloride

Produit contrôlé

CAS : 1217623-74-9

Formule : CC₁₅H₁₇BrCl₁₅N₂NO₃·HCl

Couleur et forme : Neat

Masse moléculaire : 454.122

Ref: TR-H102502

Halofuginone hydrochloride

CAS : 1217623-74-9

Halogenated derivative of febrifugine; coccidiostat

Formule : C₁₆H₁₇BrClN₃O₃·HCl

Degré de pureté : Min. 95%

Couleur et forme : White To Off-White Solid

Masse moléculaire : 451.14 g/mol

Ref: 3D-FH23732

Halofuginone hydrochloride

CAS : 1217623-74-9

Halofuginone hydrochloride (RU-19110), a derivative of Febrifugine, functions as a competitive inhibitor of prolyl-tRNA synthetase, displaying a Ki value of 18.3 nM. This compound effectively inhibits type-I collagen synthesis, providing therapeutic benefits in osteoarthritis (OA) by impeding TGF-β signaling. Additionally, it serves as a potent pulmonary vasodilator, mainly through the activation of Kv channels and the inhibition of various calcium channels including voltage-gated, receptor-operated, and store-operated ones. Beyond its vascular effects, Halofuginone hydrochloride exhibits a broad spectrum of biological activities, including anti-malarial, anti-inflammatory, anti-cancer, and anti-fibrotic properties, supported by multiple studies.

Formule : C₁₆H₁₈BrCl₂N₃O₃

Couleur et forme : Solid

Masse moléculaire : 451.14

Ref: TM-T84443