CAS 1217837-17-6

5-Iodo-A-85380 (dihydrochloride)

CAS : 1217837-17-6

5-Iodo-A-85380 (dihydrochloride)

Degré de pureté : 98%

Masse moléculaire : 363.02g/mol

Ref: 54-OR1035896

5-IODO-A-85380 Dihydrochloride

Produit contrôlé

CAS : 1217837-17-6

Applications 5-IODO-A-85380 Dihydrochloride is a highly potent and subtype-selective agonist for AChR α4β2 and AChR α6β2.
References Koren, A.O., et al.: J. Med. Chem., 41, 3690-3698 (1998); Muhkin, A.G., et al.: Mol. Pharmacol., 57, 642-649 (2000); Mogg, A.J., et al.: Neuropharmacology, 47, 848-859 (2004);

Formule : C₉H₁₁IN₂O·2HCl

Couleur et forme : Neat

Masse moléculaire : 363.02

Ref: TR-I737008

(S)-3-(Azetidin-2-ylmethoxy)-5-iodopyridine dihydrochloride

CAS : 1217837-17-6

5-Iodo-A-85380 dihydrochloride is an acetylcholine antagonist that blocks nicotinic acetylcholine receptors. It is used to study the function of acetylcholine and cholinergic synapses in animals. 5-Iodo-A-85380 dihydrochloride is also used to study the effects of drugs on αβ nicotinic receptors and glutamate receptors. This drug binds to extracellular Ca2+, which reduces its effect on these receptors. It has been shown to decrease synaptic activity in rats, with a dose dependent response. 5-Iodo-A-85380 dihydrochloride has an inhibitory effect on fluorimetric assays for glutamate and amino acids, indicating that it may be useful in studies of neurotransmitter release.

Formule : C₉H₁₁IN₂O·2HCl

Degré de pureté : Min. 95%

Couleur et forme : Powder

Masse moléculaire : 363.03 g/mol

Ref: 3D-SYB83717

5-Iodo-A-85380 dihydrochloride

CAS : 1217837-17-6

α4β2 and α6β2 nicotinic acetylcholine receptors agonist

Formule : C₉H₁₃Cl₂IN₂O

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 363.02

Ref: TM-T22521