CAS 1254053-84-3

6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide (2E)-2-butenedioate (2:1)

CAS : 1254053-84-3

Formule : C₃₇H₅₂N₈O₁₁

Degré de pureté : 99.75%

Couleur et forme : Solid

Masse moléculaire : 784.8558

Ref: IN-DA000NMO

Gilteritinib hemifumarate

CAS : 1254053-84-3

Gilteritinib hemifumarate

Degré de pureté : ≥98%

Masse moléculaire : 610.75g/mol

Ref: 54-BUP00922

Gilteritinib hemifumarate

CAS : 1254053-84-3

Gilteritinib hemifumarate is a bioavailable inhibitor of CTLA-4, which is a receptor for the protein CD80. This protein is expressed on the surface of T cells and plays an important role in regulating the immune system. Gilteritinib hemifumarate has been shown to induce regression in some cancers, such as ovarian cancer, by inhibiting the growth of cancer cells. It also induces apoptosis in leukemia stem cells and monoclonal antibodies that target CD80. This drug binds to CTLA-4 and blocks its inhibitory activity on CD28, which promotes T cell activation.

Formule : C₆₂H₉₂N₁₆O₁₀

Degré de pureté : Min. 95%

Masse moléculaire : 1,221.5 g/mol

Ref: 3D-EAC05384

Gilteritinib hemifumarate

CAS : 1254053-84-3

Gilteritinib hemifumarate (ASP2215 hemifumarate) is a potent ATP-competitive dual FLT3 (IC50: 0.29 nM) and AXL (IC50: 0.73 nM) inhibitor for the treatment of

Formule : C₂₉H₄₄N₈O₃C₄H₄O₄

Degré de pureté : 99.78%

Couleur et forme : Solid

Masse moléculaire : 610.75

Ref: TM-T71973