CAS 1254507-01-1

GKT136901 hydrochloride

CAS : 1254507-01-1

GKT136901 hydrochloride

Degré de pureté : ≥95%

Masse moléculaire : 403.26g/mol

Ref: 54-BUP21742

GKT136901 hydrochloride

CAS : 1254507-01-1

GKT136901 HCl: Potent, selective NOX1/4 inhibitor, K i of 160/165 nM, combats diabetic complications, stroke, and inflammation.

Formule : C₁₉H₁₆Cl₂N₄O₂

Couleur et forme : Solid

Masse moléculaire : 403.26

Ref: TM-T38646

GKT136901 hydrochloride

CAS : 1254507-01-1

GKT136901 is a potent, selective, and orally bioavailable small molecule that activates the G protein-coupled receptor GPR35. It has been shown to have minimal effect on other receptors. This agent has been shown to be an effective inhibitor of the bacterial enzyme phosphodiesterase 4 (PDE4) with IC50 values of 0.1 nM and 0.5 nM in human cells, respectively. It also inhibits the activity of the human PDE4D3 isoform with an IC50 value of 10 nM in vitro.

Formule : C₁₉H₂₀Cl₂N₄O₂

Degré de pureté : Min. 95%

Masse moléculaire : 407.3 g/mol

Ref: 3D-EAC50701