CAS 1263176-34-6

4-Hydroxy Atorvastatin Hemicalcium Salt

CAS : 1263176-34-6

Applications 4-Hydroxyatorvastatin is a hydroxylated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
References Smith, S. et al.: Am. J. Cardiol., 80, 10H (1997); Jacobsen, W. et al.: Drug Metab. Dispos., 28, 1369 (2000); Istvan, E. et al.: Science, 292, 1160 (2001); Tabernero, L. et al.: J. Biol. Chem., 278, 19933 (2003); Bratton, L. et al.: Bioorg. Med. Chem., 15, 5576 (2007);

Formule : C₆₆H₆₈CaF₂N₄O₁₂

Degré de pureté : >90%

Couleur et forme : Neat

Masse moléculaire : 1187.34

Ref: TR-H828961

4-Hydroxy Atorvastatin

CAS : 1263176-34-6

Formule : C₃₃H₃₄FN₂O₆(Ca)

Masse moléculaire : 573.6 : 1/2(40.1)

Ref: ST-EA-CP-A32087