CAS 1268610-38-3

3,17-Diiodoandrosta-3,5,16-triene

Produit contrôlé

CAS : 1268610-38-3

Applications 3,17-Diiodoandrosta-3,5,16-triene is used in the synthesis of 3,17-Dicarboxamido-androst-3,5,16-triene via palladium-catalyzed aminocarbonylation. It is an Abiraterone 3-iodine impurity. Abiraterone is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
References Acs, Peter., et al.: Steroids, 76, 280(2011); Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389 (2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005);

Formule : C₁₉H₂₄I₂

Couleur et forme : Neat

Masse moléculaire : 506.203

Ref: TR-D126860

Abiraterone 3-Iodine

CAS : 1268610-38-3

Formule : C₁₉H₂₄I₂

Masse moléculaire : 506.21

Ref: ST-EA-CP-A67027