CAS 1282549-08-9

ASP 6432

CAS : 1282549-08-9

Potent antagonist of type 1 receptor lysophosphatidic acid (LPA1), selective over other LPA subtypes at least by ten-fold. Blocks LPA-induced contraction in urethra and prostate, as well as proliferation of prostatic stromal cells. These findings indicate a potential use of ASP 6432 for the treatment of lower urinary tract symptoms and benign prostatic hyperplasia (LUTS/BPH).

Formule : C₂₆H₃₁N₄O₆S₂·K

Degré de pureté : Min. 95%

Masse moléculaire : 598.78 g/mol

Ref: 3D-BA167271

ASP6432

CAS : 1282549-08-9

ASP6432 is an antagonist of type 1 lysophosphatidic acid receptor (LPA1). For human LPA1 and rat LPA1, the IC50s are 11 nM and 30 nM , respectively.

Formule : C₂₆H₃₂KN₄O₆S₂

Couleur et forme : Solid

Masse moléculaire : 599.78

Ref: TM-T14335