CAS 1296212-29-7

5-Dehydro Tolvaptan-d7

Produit contrôlé

CAS : 1296212-29-7

Applications 5-Dehydro Tolvaptan-d7 is an intermediate in synthesizing Tolvaptan-d7 (T536652), a labelled Tolvaptan. It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).
References Paterna, S., et al.: Eur. J. Heart Fail, 2, 305 (2000); Udelson, J., et al.: Circulation, 104, 2417 (2001); Goldsmith, S., et al.: J. Am. Coll Cardiol., 46, 1785 (2005); Schrier, R., et al.: N. Engl. J. Med., 355, 2099 (2006)

Formule : C₂₆H₁₆D₇ClN₂O₃

Couleur et forme : Neat

Masse moléculaire : 453.97

Ref: TR-D230352