CAS 130-61-0
:Chlorhydrate de thioridazine
Description :
Chlorhydrate de thioridazine est un médicament antipsychotique principalement utilisé pour traiter la schizophrénie et d'autres troubles psychotiques. Il appartient à la classe des composés phénothiaziniques, caractérisés par une structure à trois anneaux incluant un atome de soufre. La thioridazine agit principalement comme un antagoniste de la dopamine, bloquant les récepteurs de dopamine dans le cerveau, ce qui aide à atténuer les symptômes de la psychose. La forme de sel hydrochlorique améliore sa solubilité et sa stabilité. En termes de caractéristiques physiques, Chlorhydrate de thioridazine est typiquement une poudre cristalline blanche à blanc cassé. Il est soluble dans l'eau et l'alcool, avec un point de fusion relativement bas. Le composé peut présenter des effets secondaires, notamment de la sédation, des effets anticholinergiques et des problèmes cardiovasculaires potentiels, nécessitant une surveillance attentive pendant le traitement. De plus, la thioridazine a été associée à un risque de prolongation de l'intervalle QT, ce qui peut entraîner des troubles graves du rythme cardiaque. Comme pour tout médicament, il est essentiel d'utiliser Chlorhydrate de thioridazine sous la direction d'un professionnel de la santé, en tenant compte de ses avantages thérapeutiques et de ses risques potentiels.
Formule :C21H26N2S2·ClH
InChI :InChI=1S/C21H26N2S2.ClH/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23;/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3;1H
Code InChI :InChIKey=NZFNXWQNBYZDAQ-UHFFFAOYSA-N
SMILES :C(CC1N(C)CCCC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(SC)C3.Cl
Synonymes :- 10-(2-(1-Methyl-2-Piperidinyl)Ethyl)-2-(Methylthio)-10H-Phenothiazinmono
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazinmonohydrochl
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylthiophenothiazinehydrochloride
- 10-[2-(1-Methyl-2-Piperidyl)-Ethyl]-2-[Methylthiol]-Phenothiazine Hydrochloride
- 10-[2-(1-Methyl-2-Piperidyl)Ethyl]-2-(Methylthio)-10H-Phenothiazine Hydrochloride
- 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride
- 10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride
- 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride (1:1)
- 10-[3-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine hydrochloride
- 10H-Phenothiazine, 10-2-(1-methyl-2-piperidinyl)ethyl-2-(methylthio)-, monohydrochloride
- 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, hydrochloride (1:1)
- 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, monohydrochloride (9CI)
- 2-Methylmercapto-10-[2-(N-methyl-2-piperidyl)ethyl]phenothiazine Hydrochloride
- 2-methylmercapto-10-(2-(n-methyl-2-piperidyl)ethyl)phenothiazinehydrochlorid
- Aldazine
- Labotest-Bb Lt00451961
- Mallorol
- Mellaril
- Mellaril hydrochloride
- Melleretten
- Melleril
- NSC 186060
- Novoridazine
- Orsanil
- Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)-, hydrochloride
- Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)-, monohydrochloride
- Ridazin
- Stalleril
- THIORIDAZINEHYDROCHLORIDE,USP
- ThioridazinHCl
- Thioridazine Hcl
- Thioridazinhydrochlorid
- Thioril
- Thiozine
- mellarilhydrochloride
- melleril(tablet)
- usafsz-3
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazinmonohydrochl
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylthiophenothiazinehydrochloride
- 2-methylmercapto-10-(2-(n-methyl-2-piperidyl)ethyl)phenothiazinehydrochlorid
- mellarilhydrochloride
- melleril(tablet)
- usafsz-3
- ThioridazinHCl
- Thioridazinhydrochlorid
- 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride
- 2-Methylmercapto-10-[2-(N-methyl-2-piperidyl)ethyl]phenothiazine Hydrochloride
- Orsanil
- Ridazin
- Stalleril
- 10H-Phenothiazine, 10-2-(1-methyl-2-piperidinyl)ethyl-2-(methylthio)-, monohydrochloride
- THIORIDAZINEHYDROCHLORIDE,USP
- Voir plus de synonymes
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15 produits concernés.
Thioridazine Hydrochloride
CAS :Formule :C21H26N2S2·HClDegré de pureté :>98.0%(HPLC)Couleur et forme :White to Almost white powder to crystalMasse moléculaire :407.03Thioridazine Hydrochloride 1.0 mg/ml in Methanol (as free base)
CAS :Couleur et forme :Single SolutionTHIORIDAZINE HYDROCHLORIDE CRS
CAS :THIORIDAZINE HYDROCHLORIDE CRSFormule :C21H27ClN2S2Couleur et forme :PowderMasse moléculaire :407.0355Thioridazine Hydrochloride
CAS :Antidepressants, tranquilizers and other pschotherapeutic agentsFormule :C21H26N2S2·ClHCouleur et forme :PowderMasse moléculaire :406.13042Thioridazine hydrochloride
CAS :Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4Formule :C21H27ClN2S2Degré de pureté :99.55% - 99.957%Couleur et forme :White To Off-White SolidMasse moléculaire :407.04Thioridazine HCl
CAS :Formule :C21H26N2S2·HClCouleur et forme :White To Off-White SolidMasse moléculaire :370.58 36.46Thioridazine hydrochloride
CAS :Thioridazine hydrochlorideDegré de pureté :≥98%Masse moléculaire :407.04g/molThioridazine hydrochloride
CAS :Formule :C21H26N2S2·HClDegré de pureté :≥ 98.0%Couleur et forme :White to off-white powder or crystalsMasse moléculaire :407.03Thioridazine Hydrochloride
CAS :Produit contrôléFormule :C21H26N2S2·ClHCouleur et forme :NeatMasse moléculaire :407.04Thioridazine hydrochloride
CAS :Produit contrôléFormule :C21H26N2S2·ClHCouleur et forme :NeatMasse moléculaire :407.0410-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride
CAS :10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochlorideFormule :C21H26N2S2·ClHDegré de pureté :98%Couleur et forme : white solidMasse moléculaire :407.04g/molThioridazine Hydrochloride
CAS :Produit contrôlé<p>Applications Thioridazine HCl is a dopamine receptor blocker and antipsychotic. It is the parent compound of sulforidazine and mesoridazine. This compound has been reported to bind strongly to dopamine receptors on cancer stem cells and cause differentiation leaving normal cells alone (see Can. Chem. News 12 July/August 2012).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Goldenthal, E.I., Toxicol. Appl. Pharmacol., 18, 185 (1971), Abdel-Moety, E.M., et al.: Anal. Profile Drug Subs., 18, 459 (1989),<br></p>Formule :C21H26N2S2·ClHCouleur et forme :Light YellowMasse moléculaire :407.0410-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride
CAS :Produit contrôlé<p>The drug, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride (CGP 46660), is a competitive antagonist at the human histamine H3 receptor. It has been shown to bind to the histamine H3 receptor in the range of 0.001 to 1 μM and is selective for this receptor over other receptors. CGP 46660 is an optical sensor that can be used in titration calorimetry experiments to measure changes in heat production when it binds to histamine H3 receptors. The drug also has been shown to inhibit guanine nucleotide-binding protein (G protein) signaling pathways and brain functions such as memory formation, learning, and attention span. These effects were demonstrated in humans by measuring EEG activity. The optimum concentration of CGP 46660 for these effects was found to be between 0.01 and 10 μM.</p>Formule :C21H27ClN2S2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :407.04 g/mol
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