
CAS 1309283-32-6
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3 produits concernés.
Mesalazine-d3
CAS :Produit contrôléStability Hygroscopic
Applications Mesalazine-d3, is the labeled analogue of Mesalazine (M258100), the active metabolite of Sulfasalazine (S699084). Anti-inflammatory (gastrointestinal).
References Friedman, G., et al.: Am. J. Gastroenterol., 81, 141 (1986), Tursi A., Expert Opin. Pharmacother., 6, 69 (2005)Formule :C7H4D3NO3Couleur et forme :NeatMasse moléculaire :156.15Mesalazine-d3
CAS :Produit contrôléMesalazine-d3 is a mesalazine derivative that has been prepared by the addition of a deuterium atom at the 3 position. Mesalazine-d3 is used as an ionization probe for the study of inflammatory bowel disease and as a matrix effect marker in biological samples. The addition of a deuterium atom to mesalazine-d3 increases its electron affinity, leading to increased sensitivity and selectivity in mass spectrometry. Mesalazine is a medication that reduces inflammation in the digestive tract. It is used to treat ulcerative colitis, an inflammatory bowel disease, and other conditions involving inflammation of the colon. Mesalazine binds to bacterial membrane phospholipids and alters their fluidity, which leads to reduced production of inflammatory substances such as prostaglandins. It also blocks the activity of enzymes involved in prostaglandin synthesis, including cyclooxygenase (COX) and lipoxygenase (LOXFormule :C7H4D3NO3Degré de pureté :Min. 95%Masse moléculaire :156.15 g/mol


