CAS 1312424-26-2

Rilpivirine-d6 HCl

CAS : 1312424-26-2, 700361-47-3

Formule : C₂₂H₁₂D₆N₆·HCl

Couleur et forme : Off-White Solid

Masse moléculaire : 372.46 36.46

Ref: 4Z-R-341

Rilpivirine-d6

Produit contrôlé

CAS : 1312424-26-2

Applications A labelled novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent.
References Sun, et al.: J. Med. Chem., 41, 4648 (1998); Kashiwada, et al.: Bioorg. Med. Chem. Lett., 11, 183 (2001);

Formule : C₂₂₂H₆H₁₂N₆

Couleur et forme : White To Yellow

Masse moléculaire : 372.46

Ref: TR-R509802

Rilpivirine-d6

CAS : 1312424-26-2

Rilpivirine-d6 is a deuterated, stable isotope of rilpivirine. It is used to investigate the metabolism of drugs in plasma samples and tissues for bioequivalence studies. Rilpivirine-d6 is used as an internal standard in quantitative analysis by mass spectrometry. The stability of this molecule enables it to be used in prolonged studies without significant degradation. Rilpivirine-d6 has been shown to reduce viral load and increase CD4+ T cell counts in HIV patients who are on antiretroviral therapy. Rilpivirine-d6 binds to the reverse transcriptase enzyme and prevents the formation of DNA from RNA, thus inhibiting viral replication.

Formule : C₂₂H₁₈N₆

Degré de pureté : Min. 95%

Masse moléculaire : 372.5 g/mol

Ref: 3D-MCC42426