CAS 1312815-93-2

PF-4693627

CAS : 1312815-93-2

PF-4693627 is a potent, selective, and orally active prostaglandin E2 receptor agonist with pharmacological activity at the COX-2 enzyme. PF-4693627 has been shown to be effective in reducing inflammation and pain in animal models of inflammatory diseases, such as uveitis and arthritis. PF-4693627 is also being investigated for its potential use as an analgesic in humans. This drug has been shown to have a good safety profile in clinical studies.
PF-4693627 binds selectively to the prostaglandin E2 receptor subtype EP3 (COX-2) without significant binding to EP1 or EP2 receptors. This compound was developed by Pfizer Inc., which will be conducting Phase III clinical trials on this drug.

Formule : C₂₆H₂₉Cl₂N₃O₃

Degré de pureté : Min. 95%

Masse moléculaire : 502.4 g/mol

Ref: 3D-MCC81593

PF-4693627

CAS : 1312815-93-2

PF-4693627 is an effective and selective microsomal prostaglandin E synthase-1 inhibitor (IC50=3 nM).

Formule : C₂₆H₂₉Cl₂N₃O₃

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 502.43

Ref: TM-T16504