CAS 1334294-76-6

(E)-8-(3-(4-Chlorophenyl)acryloyl)-3-(3,4-dichlorobenzyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one

CAS : 1334294-76-6

(E)-8-(3-(4-Chlorophenyl)acryloyl)-3-(3,4-dichlorobenzyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one

Degré de pureté : 99%

Masse moléculaire : 479.79g/mol

Ref: 54-OR1074809

GSK682753A

CAS : 1334294-76-6

GSK682753A is a selective and highly potent inverse agonist of the epstein-barr virus-induced receptor 2 (EBI2; IC50: 53.6 nM).

Formule : C₂₃H₂₁Cl₃N₂O₃

Couleur et forme : Solid

Masse moléculaire : 479.78

Ref: TM-T11498

GSK682753A

CAS : 1334294-76-6

GSK682753A is a synthetic molecule that inhibits the enzyme G6PD. It is an extracellular inhibitor of chemotaxis and has been shown to inhibit the growth of viruses and tissues. GSK682753A was designed to inhibit G6PD, which is an enzyme that catalyzes the conversion of NADP+ to NADPH. The inhibition of this enzyme leads to a decrease in intracellular levels of NADPH and ATP, causing a deficiency in red blood cells (RBCs). In RBCs, electron microscopic images show that G6PD deficiency leads to a reduced number of mitochondria and rough endoplasmic reticulum as well as increased numbers of lysosomes. This compound also activates follicle cells, which are involved in the production of red blood cells.

Formule : C₂₃H₂₁Cl₃N₂O₃

Degré de pureté : Min. 95%

Couleur et forme : Powder

Masse moléculaire : 479.78 g/mol

Ref: 3D-JDC29476