CAS 1335202-59-9

Febuxostat Related Compound D (2-[4-(sec-Butoxy)-3-cyanophenyl]-4-methylthiazole-5-carboxylic acid)

CAS : 1335202-59-9

Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure

Formule : C₁₆H₁₆N₂O₃S

Couleur et forme : Off-White Fine Powder

Masse moléculaire : 316.08816

Ref: 45-1269384

Febuxostat sec-butoxy acid

CAS : 1335202-59-9

Febuxostat sec-butoxy acid

Degré de pureté : 95%

Ref: 54-OR1038213

Febuxostat sec-butoxy acid

CAS : 1335202-59-9

Febuxostat sec-butoxy acid is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .

Formule : C₁₆H₁₆N₂O₃S

Couleur et forme : Solid

Masse moléculaire : 316.37

Ref: TM-T73966

Febuxostat USP Related Compound D

CAS : 1335202-59-9

Formule : C₁₆H₁₆N₂O₃S

Couleur et forme : Pale Grey Solid

Masse moléculaire : 316.38

Ref: 4Z-F-3936

Febuxostat 2-Butyl Isomer

Produit contrôlé

CAS : 1335202-59-9

Applications Febuxostat 2-butyl Isomer is an impurity of Febuxostat (F229000) which is a xanthine oxidase/xanthine dehydrogenase inhibitor.
References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)

Formule : C₁₆H₁₆N₂O₃S

Couleur et forme : Neat

Masse moléculaire : 316.37

Ref: TR-F229040

Febuxostat sec-Butyl Ether Acid Impurity

CAS : 1335202-59-9

Formule : C₁₆H₁₆N₂O₃S

Masse moléculaire : 316.38

Ref: ST-EA-CP-F7004

2-(4-(SEC-BUTOXY)-3-CYANOPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLIC ACID

CAS : 1335202-59-9

Degré de pureté : 95%

Masse moléculaire : 316.3800049

Ref: 10-F796281

Febuxostat Sec-butoxy acid

CAS : 1335202-59-9

Febuxostat is a non-peptide inhibitor of xanthine oxidase (XO), an enzyme that catalyzes the conversion of xanthine and hypoxanthine to uric acid. Febuxostat is used as a treatment for chronic gout in adults who are not adequately controlled on allopurinol alone or who cannot tolerate allopurinol. Febuxostat has been shown to be effective in inhibiting the activity of human recombinant XO, both in vitro and in vivo. The compound is a competitive inhibitor of L-histidine with an IC50 of 0.3 microM at pH 7.4 and 0.1 microM at pH 6.0, which is more potent than other peptidomimetics such as febuprofen and fexofenadine, but less potent than CGP57148B and CGP37849A.
Febuxostat has also been shown to have

Formule : C₁₆H₁₆N₂O₃S

Degré de pureté : Min. 95%

Masse moléculaire : 316.4 g/mol

Ref: 3D-KDC20259