CAS 1346601-96-4

6-Methylthioguanine-d3

Produit contrôlé

CAS : 1346601-96-4

Applications A labelled metabolite of 2’-Deoxy-6-thio Guanosine (D281650) and 6-Thioguanine. An effective immunosuppressant and anticancer agent, however chronic exposure can be mutagenic in human cells as long-term use of thiopurines was found to be associated with a significantly increased risk of various types of cancer.
References Loo, T.L. et al.: Cancer Chemother. Pharmacol., 6, 131 (1981); Yuan, B. et al.: ACS Chem. Biol., 5, 1021 (2010); Kroplin, T. et al.: Adv. Exp. Med. Biol., 431, 741 (1998);

Formule : C₆₂H₃H₄N₅S

Couleur et forme : Neat

Masse moléculaire : 184.24

Ref: TR-M330722