CAS 1355327-02-4

ML309 hydrochloride

CAS : 1355327-02-4

ML309 is an antibody that inhibits the activity of peptide ligands to ion channels. It has been shown to inhibit the binding of peptide ligands to the β-adrenergic receptor and α-adrenergic receptor in a competitive manner. This drug is a potent inhibitor of the calcium channel, but does not affect potassium channels or voltage-gated sodium channels. ML309 binds to the extracellular domain of receptors and prevents access by peptide ligands, blocking their ability to activate ion channels.

Formule : C₂₉H₂₉FN₄O₂·HCl

Degré de pureté : Min. 95%

Masse moléculaire : 521.03 g/mol

Ref: 3D-FEC32702

ML-309 (hydrochloride)

CAS : 1355327-02-4

ML-309 selectively inhibits mutant IDH1R132H over wild-type, reduces 2-HG in glioblastoma cells. IC50: 96 nM; EC50: 55 nM.

Formule : C₂₉H₃₀ClFN₄O₂

Couleur et forme : Solid

Masse moléculaire : 521.03

Ref: TM-T38004