CAS 137017-45-9

Cytidine, 2'-deoxy-5-formyl-

CAS : 137017-45-9

Formule : C₁₀H₁₃N₃O₅

Degré de pureté : 98%

Masse moléculaire : 255.2273

Ref: IN-DA0012PF

4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde

CAS : 137017-45-9

4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde

Degré de pureté : 98%

Masse moléculaire : 255.23g/mol

Ref: 54-OR1062323

2''-Deoxy-5-formylcytidine

CAS : 137017-45-9

Formule : C₁₀H₁₃N₃O₅

Degré de pureté : ≥ 98.0%

Couleur et forme : White to off-white solid

Masse moléculaire : 255.23

Ref: 7W-GW1127

2'-Deoxy-5-formyl-cytidine

Produit contrôlé

CAS : 137017-45-9

Applications 2'-Deoxy-5-formyl-cytidine is a nucleotide derivative found in embryonic stem cell DNA.
References Pfaffeneder, T., et al.: Angew. Chem. Int. Edit., 50, 7008-7012 (2011)

Formule : C₁₀H₁₃N₃O₅

Couleur et forme : Neat

Masse moléculaire : 255.227

Ref: TR-D239810

2'-Deoxy-5-formylcytidine

CAS : 137017-45-9

2'-Deoxy-5-formylcytidine is a nucleoside analog that is used as a chemotherapeutic agent. It is cytotoxic to cells by binding to DNA and preventing the synthesis of DNA, RNA, and protein. The drug has been shown to induce cellular senescence in human fibroblasts, which can be reversed by the addition of deuterium. 2'-Deoxy-5-formylcytidine also inhibits the production of reactive oxygen species (ROS) by inducing the expression of antioxidant enzymes such as superoxide dismutase 2 and glutathione peroxidase 1. The oxidation products are misincorporated into DNA strands, leading to intramolecular hydrogen bonds with cytosine bases. These modifications lead to denaturation of DNA and inhibition of transcription and replication.
2'-Deoxy-5-formylcytidine also interacts with oligodeoxynucleotides, which leads to misinc

Formule : C₁₀H₁₃N₃O₅

Degré de pureté : Min. 97 Area-%

Couleur et forme : White Powder

Masse moléculaire : 255.23 g/mol

Ref: 3D-ND63556

2'-Deoxy-5-formyl-cytidine-1,3-15N2,2-13C

Produit contrôlé

CAS : 137017-45-9

Formule : CC₉H₁₃₁₅N₂NO₅

Couleur et forme : Neat

Masse moléculaire : 258.207

Ref: TR-D239812