CAS 13784-17-3

N4-Methylpyrimidine-4,5-diamine

CAS : 13784-17-3

N4-Methylpyrimidine-4,5-diamine is an inhibitor of glycogen synthase kinase-3 (GSK3). It binds to the ATP binding site on GSK3 and inhibits its activity, which leads to a decrease in the phosphorylation of glycogen synthase. This inhibition results in a decrease in glycogen synthesis. N4-Methylpyrimidine-4,5-diamine has been shown to inhibit the catalytic activity of GSK3 with magnesium as a cofactor. It also has been shown to have antiinflammatory effects due to its ability to inhibit nitric oxide production. The compound is formed by reducing purines with sodium borohydride and then reacting it with triazole.

Formule : C₅H₈N₄

Degré de pureté : Min. 95%

Masse moléculaire : 124.14 g/mol

Ref: 3D-NAA78417