CAS 1382481-79-9

ML-289

CAS : 1382481-79-9

Formule : C₂₂H₂₃NO₃

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 349.4229

Ref: IN-DA00AAXU

ML289

CAS : 1382481-79-9

ML289

Degré de pureté : ≥98%

Masse moléculaire : 349.42g/mol

Ref: 54-BUP10435

ML289

CAS : 1382481-79-9

ML289 is an allosteric modulator of metabotropic glutamate receptors (mGluRs). It has been shown to activate mGluR2/3 and mGluR4 in vitro. ML289 is a structural analog of the amino acid glutamate and binds to the same site as glutamate. This binding leads to increased signaling through these receptors, which are involved in many physiological processes, including myotonica and physiochemical functions. ML290 has been shown to be penetrant in vivo, with high brain concentrations achieved following peripheral administration. The pharmacokinetics of ML290 have also been characterized in rats, demonstrating that it is rapidly absorbed after oral administration and its concentration remains relatively stable over time.
ML290 has also been shown to bind metal surfaces such as steel or nickel, making it a potential candidate for use on metal surfaces where bacteria may grow.

Formule : C₂₂H₂₃NO₃

Degré de pureté : Min. 95%

Masse moléculaire : 349.42 g/mol

Ref: 3D-HFC48179

ML289

CAS : 1382481-79-9

ML289 is a potent CNS-penetrant mGlu3 modulator with IC50 of 0.66 μM, >15-fold selectivity over mGlu2, and inactive against mGlu5.

Formule : C₂₂H₂₃NO₃

Degré de pureté : 99.54%

Couleur et forme : Solid

Masse moléculaire : 349.42

Ref: TM-T23000