CAS 1404-93-9
:Vancomycine, chlorhydrate
Description :
L'hydrochlorure de vancomycine est un antibiotique glycopeptidique principalement utilisé pour traiter des infections bactériennes graves, en particulier celles causées par des bactéries Gram-positives, y compris Staphylococcus aureus résistant à la méthicilline (MRSA). Il se caractérise par sa structure complexe, qui comprend une série d'acides aminés et de groupes de sucre qui contribuent à son mécanisme d'action. La vancomycine agit en inhibant la synthèse de la paroi cellulaire dans les bactéries, entraînant finalement la lyse cellulaire et la mort. La forme hydrochlorure améliore sa solubilité dans l'eau, ce qui la rend adaptée à l'administration intraveineuse. Elle est généralement administrée dans un cadre clinique en raison de sa puissance et de la nécessité de surveiller les effets secondaires potentiels, tels que la néphrotoxicité et l'ototoxicité. La vancomycine est également remarquable pour son spectre d'activité, qui est limité à certains types de bactéries, et elle est souvent réservée aux cas où d'autres antibiotiques sont inefficaces. Son utilisation est guidée par des tests de sensibilité pour garantir son efficacité et lutter contre le développement de la résistance aux antibiotiques.
Formule :C66H75Cl2N9O24·xClH
InChI :InChI=1S/C66H75Cl2N9O24.ClH/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92;/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95);1H/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-;/m0./s1
Code InChI :InChIKey=LCTORFDMHNKUSG-XTTLPDOESA-N
SMILES :O(C=1C2=CC3=CC1OC=4C(Cl)=CC(=CC4)[C@@H](O)[C@@H](NC([C@@H](CC(C)C)NC)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@]3(C(=O)N[C@@]5(C=6C=C(C=7C([C@@H](C(O)=O)NC(=O)[C@]([C@H](O)C=8C=C(Cl)C(O2)=CC8)(NC5=O)[H])=CC(O)=CC7O)C(O)=CC6)[H])[H])[C@H]9[C@H](O[C@H]%10C[C@](C)(N)[C@H](O)[C@H](C)O%10)[C@@H](O)[C@H](O)[C@@H](CO)O9.Cl
Synonymes :- (1S,2R,18R,19R,22S,25R,28R,40S)-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[(2R)-4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.23,6.214,17.18,12.129,33.010,25.034,39]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid hydrochloride (non-preferred name)
- (1S,2R,18R,19R,22S,25R,28R,40S)-48-{[(2S,3R,4S,5S,6R)-3-{[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[(2R)-4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2~3,6~.2~14,17~.1~8,12~.1~29,33~.0~10,25~.0~34,39~]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid (non-preferred name)
- (3S-(3R*,6S*(S*),7S*,22S*,23R*,26R*,36S*,38aS*))-3-(2-Amino-2-oxoethyl)-44-((2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyl)oxy)-10,19-dichloro-2,3,4,5,6,7,23,24,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-((4-methyl-2-(methylamino)-1-oxopentyl)amino)-2,5,24,38,39-pentaoxo-22H-8,11:18,21-dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno-1H,16H-(1,6,9)oxadiazacyclohexadecino(4,5-m)(10,2,16)benzoxadiazacyclotetracosine-26-carboxylic acid, monohydrochloride
- 22H-8,11:18,21-Dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno-1H,16H-[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine, vancomycin deriv.
- 48-({3-[(4-amino-5-hydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy]-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl}oxy)-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-{[4-methyl-2-(methylamino)pentanoyl]amino}-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentaazaoctacyclo[26.14.2.2~3,6~.2~14,17~.1~8,12~.1~29,33~.0~10,25~.0~34,39~]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid hydrochloride (1:1) (non-preferred name)
- Laikexin
- Lyphocin
- Unii-71Wo621Tjd
- Vancocin hydrochloride
- Vancocine hydrochloride
- Vancocyn
- Vancomycin HCl
- Vancomycin monohydrochloride
- Vancor
- Voir plus de synonymes
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25 produits concernés.
Vancomycin hydrochloride, Molecular Biology Grade
CAS :Vancomycin hydrochloride, 1404-93-9, is a polypeptide with antibiotic properties suitable for laboratory study of bacterial infections. Learn more at Thermo Fisher Scientific.Formule :C66H76Cl3N9O24Couleur et forme :White to tan to brown, Free-flowing powderMasse moléculaire :1485.72Vancomycin hydrochloride, 50 mg/ml in distilled water, sterile-filtered
CAS :This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo SciSECOND INTERNATIONAL STANDARD FOR VANCOMYCIN
CAS :SECOND INTERNATIONAL STANDARD FOR VANCOMYCINFormule :C66H75Cl2N9O24Masse moléculaire :1449.254VANCOMYCIN HYDROCHLORIDE CRS
CAS :VANCOMYCIN HYDROCHLORIDE CRSFormule :C66H75Cl2N9O24Couleur et forme :White. Powder.Masse moléculaire :1449.254Vancomycin B
CAS :Antibiotics nesoiFormule :C66H75Cl2N9O24·HClCouleur et forme :White Brown PowderMasse moléculaire :1483.40688Vancomycin B with Monodechlorovancomycin
CAS :Diagnostic or lab reagents on a backing, prepared diagnostic or lab reagents whether or not on a backing, whether or not in the form of kits, nesoiFormule :C66H75Cl2N9O24·HClCouleur et forme :Off-White Tan PowderMasse moléculaire :1483.40688Vancomycin, hydrochloride
CAS :Formule :C66H76Cl3N9O24Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :1485.7145Vancomycin hydrochloride
CAS :Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!Formule :C66H76Cl3N9O24Degré de pureté :97.20% - 99.19%Couleur et forme :Off White PowderMasse moléculaire :1485.71Vancomycin hydrochloride
CAS :Vancomycin hydrochlorideFormule :C66H75Cl2N9O24·ClHDegré de pureté :Heavy metals: <30 ppm. (Typical Value in Batch COA)Couleur et forme : white. almost white or tan to brown free flowing powderMasse moléculaire :1,485.71g/molVancomycin hydrochloride, low endotoxin
CAS :Formule :C66H75Cl2N9O24·HClDegré de pureté :≤ 5.0%Couleur et forme :White to tan powderMasse moléculaire :1485.73Vancomycin hydrochloride BioChemica
CAS :Vancomycin hydrochloride BioChemicaCouleur et forme :SolidMasse moléculaire :1,485.71g/molVancomycin hydrochloride
CAS :Formule :C66H75Cl2N9O24·HClDegré de pureté :≤ 5.0%Couleur et forme :White to tan powderMasse moléculaire :1485.73Vancomycin hydrochloride (Standard)
CAS :Vancomycin hydrochloride (Standard) is the standard substance of Vancomycin hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Vancomycin hydrochloride (Vancomycin HCl) is a glycopeptide antibiotic that targets Peptidoglycan in bacterial cell wall synthesis. Vancomycin hydrochloride is mainly used for the treatment of severe Gram-positive bacterial infections.Formule :C66H76Cl3N9O24Couleur et forme :Off White PowderMasse moléculaire :1485.71Vancomycin hydrochloride
CAS :Produit contrôléFormule :C66H75Cl2N9O24·ClHCouleur et forme :NeatMasse moléculaire :1485.71Vancomycin Hydrochloride
CAS :Produit contrôléFormule :C66H75Cl2N9O24·ClHCouleur et forme :NeatMasse moléculaire :1485.71Vancomycin solution
CAS :Vancomycin solutionCouleur et forme :SolutionMasse moléculaire :1,485.71g/molVancomycin Hydrochloride (90%)
CAS :Stability Hygroscopic
Applications Vancomycin Hydrochloride is an antibiotic used against gram-positive bacterial strains.
References Yao, N., et al.: Biopolymers, 90, 421 (2008); Lai, H., et al.: ACS Appl. Mater. Interfaces, 7, 2046 (2015);Formule :C66H75Cl2N9O24·ClHDegré de pureté :90%Couleur et forme :NeatMasse moléculaire :1485.71Vancomycin hydrochloride, Antibiotic for Culture Media Use Only
CAS :Vancomycin hydrochloride is an antibiotic that is used against Gram-positive bacteria, including Staphylococcus aureus. It has been shown to inhibit the growth of bacteria by binding the D-alanyl-D-alanine moiety of the peptidoglycan cell wall precursor, inhibiting the peptidoglycan synthesis and disrupting its cross linking. It also inhibits particle formation when it reacts with human plasma, which can lead to hemolysis and hemagglutination. The absorption spectrum for vancomycin hydrochloride shows maxima at 230, 260, 290, and 320 nm, which are characteristic for this compound. Vancomycin has been used in several studies for treatment of methicillin-resistant Staphylococcus aureus infections.
Formule :C66H76Cl3N9O24Masse moléculaire :1,485.71 g/molRef: 3D-Q-201920
25gÀ demander50gÀ demander100gÀ demander250gÀ demander500gÀ demander-Unit-ggÀ demanderVancomycin hydrochloride
CAS :Inhibitor of cell wall biogenesis; glycopeptide antibiotic
Formule :C66H76Cl3N9O24Degré de pureté :Min. 88 Area-%Couleur et forme :PowderMasse moléculaire :1,485.71 g/molVancomycin Hydrochloride (VNC), 90%
CAS :Formule :C66H75CI2N9O24·HCIDegré de pureté :min. 90%Couleur et forme :Off white to Light pink to Orange brown, Crystalline powder, ClearMasse moléculaire :1485.73Vancomycin HCl - pharma grade
CAS :Vancomycin is a tricyclic glycopeptide antibiotic that has bactericidal effects against staphylococci, streptococci, and other gram-positive bacteria. It is often used as an alternative treatment for severe staphylococcal and streptococcal infections, including endocarditis, and infections with MRSA (methicillin-resistant Staphylococcus aureus), penicillin-resistant pneumococci or in cases of allergy to penicillins and cephalosporins.
Formule :C66H75Cl2N9O24·HClCouleur et forme :PowderMasse moléculaire :1,485.71 g/molVancomycin hydrochloride (1:1)
CAS :Vancomycin hydrochloride (1:1) is a glycopeptide antibiotic with action on bacterial cell wall synthesis and is used for treating severe bacterial infections like septicemia, endocarditis, and skin infections.
Formule :C66H76Cl3N9O24Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :1,485.72 g/molRef: 3D-XHA63825
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