CAS 1416446-40-6
:Ethyl 3-(2-(((4-(N-(ethoxycarbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate (Dabigatran Impurity)
CAS :Ethyl 3-(2-(((4-(N-(ethoxycarbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate (Dabigatran Impurity)Degré de pureté :97%Masse moléculaire :571.63g/molEthyl 3-(2-(((4-(N-(ethoxycarbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate (Dabigatran Impurity)
CAS :Degré de pureté :97%Masse moléculaire :571.638N-Ethoxycarbonyl Dabigatran Ethyl Ester
CAS :Produit contrôléApplications N-Ethoxycarbonyl Dabigatran Ethyl Ester is an impurity of Dabigatran (D100090), which is antithrombotic drug.
References Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002); Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002); Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005);Formule :C30H33N7O5Couleur et forme :NeatMasse moléculaire :571.63N-Ethoxycarbonyl dabigatran ethyl ester
CAS :N-Ethoxycarbonyl dabigatran ethyl ester is a synthetic compound that is an impurity in the drug product, Dabigatran etexilate (CAS No. 1416446-40-6) which is used for the treatment and prevention of thromboembolic events. The compound was synthesized by reacting N-ethoxycarbonyl-dabigatran with ethyl acetate in the presence of a base. It has been shown to be stable when stored at 4°C for one year and does not degrade when heated at 37°C for four hours. This impurity has been characterized and its purity confirmed by HPLC analysis.
Formule :C30H33N7O5Degré de pureté :Min. 95%Masse moléculaire :571.63 g/mol
