CAS 1417997-93-3

HDAC8-IN-1

CAS : 1417997-93-3

Formule : C₂₂H₁₉NO₃

Degré de pureté : 99%

Couleur et forme : Solid

Masse moléculaire : 345.3912

Ref: IN-DA01EO5Q

(E)-N-Hydroxy-3-(5-methoxy-[1,1':4',1''-terphenyl]-2-yl)acrylamide

CAS : 1417997-93-3

(E)-N-Hydroxy-3-(5-methoxy-[1,1':4',1''-terphenyl]-2-yl)acrylamide

Degré de pureté : 99%

Masse moléculaire : 345.39g/mol

Ref: 54-OR1023051

HDAC8-IN-1

CAS : 1417997-93-3

HDAC8-IN-1

Degré de pureté : ≥95%

Masse moléculaire : 345.39g/mol

Ref: 54-BUP15198

HDAC8-IN-1

CAS : 1417997-93-3

MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines.

Formule : C₂₂H₁₉NO₃

Degré de pureté : 97.13% - 99.19%

Couleur et forme : Solid

Masse moléculaire : 345.39

Ref: TM-T7082

HDAC8-IN-1

CAS : 1417997-93-3

HDAC8-IN-1 is a small molecule inhibitor of class I histone deacetylases (HDACs). It is a potent inhibitor of HDAC8, the most abundant HDAC in the human genome. In vitro studies have shown that HDAC8-IN-1 inhibits self-renewal and differentiation of cancer stem cells. In vivo, HDAC8-IN-1 treatment inhibited tumor growth in mouse models of leukemia and breast cancer. The pharmacological inhibition of HDAC8 with HDAC8-IN-1 has been shown to inhibit expression of genes involved in cell cycle regulation, angiogenesis, metastasis, and immune suppression.

Formule : C₂₂H₁₉NO₃

Degré de pureté : Min. 95%

Masse moléculaire : 345.39 g/mol

Ref: 3D-SGC99793