CAS 1445592-86-8

Saxagliptin Impurity 10

CAS : 1445592-86-8

Formule : C₁₁H₁₈N₂O₃

Masse moléculaire : 226.28

Ref: 4Z-S-3218

tert-Butyl (1R,3S,5R)-3-Carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate

Produit contrôlé

CAS : 1445592-86-8

Applications tert-Butyl (1R,3S,5R)-3-Carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate is an intermediate in the synthesis of ((2S,2R’,trans)-Saxagliptin (S143495), which is an impurity of Saxagliptin (S143500). Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-IV) developed for the treatment of type 2 diabetes.
References Dong, J., et al.: Bioorg. Med. Chem., 22, 1383 (2014); Feng, J., et al.: J. Med. Chem., 50, 2297 (2007); Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008); Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008)

Formule : C₁₁H₁₈N₂O₃

Couleur et forme : Neat

Masse moléculaire : 226.28

Ref: TR-B692935

Saxagliptin Impurity 27

CAS : 1445592-86-8

Formule : C₁₁H₁₈N₂O₃

Masse moléculaire : 226.28

Ref: ST-EA-CP-S19054