CAS 149286-90-8

(Z)-RG-13022

CAS : 149286-90-8

(Z)-RG-13022 is a tyrosine kinase (TK) inhibitor that preferentially inhibits the TK activity of the EGF receptor, restricting the EGF-stimulated growth of cultured cells. It demonstrates an IC50 of 11 μM for DNA synthesis in HN5 cells, showcasing thrice the potency of its isomer, (E)-RG-13022 (IC50 = 38 μM). This compound is applied in breast cancer cell research [1] [2].

Formule : C₁₆H₁₄N₂O₂

Couleur et forme : Solid

Masse moléculaire : 266.29

Ref: TM-T84525

RG-13022

CAS : 149286-90-8

RG-13022 is an ion channel inhibitor that blocks the N-type calcium channels in neuronal cells. It has been shown to be a potent and selective blocker of these channels, with little or no effect on other types of ion channels. RG-13022 is a tool for research in pharmacology, cell biology and neurobiology. It can also be used as an antibody and peptide probe. RG-13022 is a high purity compound with CAS No. 149286-90-8.

Formule : C₁₆H₁₄N₂O₂

Degré de pureté : Min. 95%

Masse moléculaire : 266.29 g/mol

Ref: 3D-ZFA28690