CAS 150322-43-3

Prasugrel

Description :

Prasugrel est un médicament antiplaquettaire principalement utilisé pour réduire le risque d'événements cardiovasculaires chez les patients présentant un syndrome coronarien aigu subissant une intervention coronarienne percutanée. C'est un dérivé de la thiénopyridine qui agit en inhibant de manière irréversible le récepteur P2Y12 sur les plaquettes, empêchant ainsi l'agrégation plaquettaire. Prasugrel se caractérise par sa rapide absorption et sa conversion en un métabolite actif, ce qui améliore son efficacité par rapport à d'autres agents antiplaquettaires. La formule chimique de Prasugrel est C20H20FNO3S, et son poids moléculaire est d'environ 343,44 g/mol. La substance est généralement administrée sous forme de pro-médicament, nécessitant une activation métabolique pour exercer ses effets thérapeutiques. Prasugrel est connu pour sa pharmacocinétique et sa pharmacodynamie relativement prévisibles, ce qui en fait un choix privilégié dans certains contextes cliniques. Cependant, il est associé à un risque accru de saignement, nécessitant une sélection et un suivi attentifs des patients. Son profil de sécurité et d'efficacité a été établi par le biais de divers essais cliniques, contribuant à son acceptation dans la pratique clinique pour la gestion des événements cardiovasculaires thrombotiques.

Formule : C₂₀H₂₀FNO₃S

InChI : InChI=1S/C20H20FNO3S/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21/h2-5,10,13,19H,6-9,11H2,1H3

Code InChI : InChIKey=DTGLZDAWLRGWQN-UHFFFAOYSA-N

SMILES : C(C(=O)C1CC1)(N2CC3=C(CC2)SC(OC(C)=O)=C3)C4=C(F)C=CC=C4

Synonymes :

• 2-Acetoxy-5-(α-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno-[3,2-c]pyridine
• 2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone
• 5-[2-Cyclopropyl-1-(2-Fluorophenyl)-2-Oxoethyl]-4,5,6,7-
• Acetic acid 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl ester
• Cs 747
• Effient free base
• Ethanone, 2-(2-(acetyloxy)-6,7-dihydrothieno(3,2-c)pyridin-5(4H)-yl)-1-cyclopropyl-2-(2-fluorophenyl)-
• Ly 640315
• Prasugrel Base
• Prasugrel [INN]
• Tetrahydrothieno[3,2-C]Pyridin-2-Yl Acetate
• Thieno[3,2-c]pyridine, ethanone deriv.
• [5-[2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate
• [5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxo-ethyl]-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-yl] acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• Prasugrel
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-
• tetrahydrothieno[3,2-c]pyridin-2-yl acetate
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-

Prasugrel

CAS : 150322-43-3

Formule : C₂₀H₂₀FNO₃S

Degré de pureté : >98.0%(T)(HPLC)

Couleur et forme : Light yellow to Yellow to Orange powder to crystal

Masse moléculaire : 373.44

Ref: 3B-P2040

2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone

CAS : 150322-43-3

Formule : C₂₀H₂₀FNO₃S

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 373.4411

Ref: IN-DA001MIM

Prasugrel

CAS : 150322-43-3

Prasugrel (CS-747) is a piperazine derivative and PLATELET AGGREGATION INHIBITOR that is used to prevent THROMBOSIS in patients with ACUTE CORONARY SYNDROME;

Formule : C₂₀H₂₀FNO₃S

Degré de pureté : 99.62% - 99.82%

Couleur et forme : White Solid

Masse moléculaire : 373.44

Ref: TM-T0230

Prasugrel

CAS : 150322-43-3

Formule : C₂₀H₂₀FNO₃S

Couleur et forme : Off-White Solid

Masse moléculaire : 373.44

Ref: 4Z-P-391

Prasugrel

CAS : 150322-43-3

Prasugrel

Degré de pureté : 99%

Masse moléculaire : 373.44g/mol

Ref: 54-PC109116

Prasugrel

CAS : 150322-43-3

Prasugrel

Degré de pureté : ≥98%

Masse moléculaire : 373.44g/mol

Ref: 54-BUP15051

Prasugrel

CAS : 150322-43-3

Formule : C₂₀H₂₀FNO₃S

Masse moléculaire : 373.44

Ref: 7W-GP4257

(±)-Prasugrel-d3 (acetate-d3)

CAS : 1127253-02-4, 150322-43-3

Degré de pureté : 99 atom % D

Couleur et forme : Off White Solid

Masse moléculaire : 376.46

Ref: 3U-D7536

Prasugrel

CAS : 150322-43-3

Degré de pureté : 95.0%

Couleur et forme : Solid

Masse moléculaire : 373.44000244140625

Ref: 10-F390330

Prasugrel - Bio-X ™

CAS : 150322-43-3

Prasugrel is a thienopyridine prodrug that inhibits the enzyme ADP-dependent P2Y purinergic receptor. Prasugrel inhibits platelet aggregation and the formation of blood clots by blocking the conversion of ADP to ATP on the surface of platelets, thus preventing the release of serotonin from platelets. The reaction products formed by prasugrel are similar to those formed by clopidogrel and include hydrogen sulfate ions and a thiol-containing metabolite. It has also been shown to have potent cytotoxic activity against melanoma cells and anti-inflammatory properties. 
Prasugrel is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formule : C₂₀H₂₀FNO₃S

Degré de pureté : (%) Min. 95%

Masse moléculaire : 373.44 g/mol

Ref: 3D-BP164290

Prasugrel

CAS : 150322-43-3

Prasugrel is a thienopyridine prodrug that inhibits the enzyme ADP-dependent P2Y purinergic receptor. Prasugrel inhibits platelet aggregation and the formation of blood clots by blocking the conversion of ADP to ATP on the surface of platelets, thus preventing the release of serotonin from platelets. The reaction products formed by prasugrel are similar to those formed by clopidogrel and include hydrogen sulfate ions and a thiol-containing metabolite. It has also been shown to have potent cytotoxic activity against melanoma cells and anti-inflammatory properties.

Formule : C₂₀H₂₀FNO₃S

Degré de pureté : Min. 95%

Couleur et forme : Powder

Masse moléculaire : 373.44 g/mol

Ref: 3D-FP10815

Prasugrel

CAS : 150322-43-3

Applications Prasugrel is a platelet inhibitor that reduces aggregation of platelets by being a P2Y12(ADP receptor) inhibitor.

Formule : C₂₀H₂₀FNO₃S

Couleur et forme : Neat

Masse moléculaire : 373.44

Ref: TR-P701188