CAS 1562406-27-2

Fosgemcitabine palabenamide

CAS : 1562406-27-2

Fosgemcitabine is a peptide analog that binds to the active site of the DNA ligase, an enzyme involved in DNA repair. Fosgemcitabine has been shown to inhibit the enzymatic activity of DNA ligase and lead to cell death by inhibiting protein synthesis and cell division. Fosgemcitabine is also known as palabenamide, which is a synthetic compound that acts as a selective inhibitor of the ion channel TRPM2. The binding of palabenamide to TRPM2 leads to inhibition of calcium influx into cells and subsequent cell death. Palabenamide has been shown to inhibit the proliferation of human T-cells and suppress antigen-specific immune responses in mice models.

Formule : C₂₅H₂₇F₂N₄O₈P

Degré de pureté : Min. 95%

Masse moléculaire : 580.5 g/mol

Ref: 3D-MMC40627