CAS 1564266-03-0

(1S,3R,5S,2’R)-Saxagliptin

CAS : 1564266-03-0

Formule : C₁₈H₂₅N₃O₂

Masse moléculaire : 315.42

Ref: 4Z-S-3245

(2’R,2R,trans)-Saxagliptin

Produit contrôlé

CAS : 1564266-03-0

Applications (2’R,2R,trans)-Saxagliptin is an impurity of Saxagliptin (S143500); a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-IV) developed for the treatment of type 2 diabetes.
References Dong, J., et al.: Bioorg. Med. Chem., 22, 1383 (2014); Feng, J., et al.: J. Med. Chem., 50, 2297 (2007); Rosenstock, J., et al.: Diabetes Obes. Metab., 10, 376 (2008); Thomas, L., et al.: J. Pharmacol. Exp. Ther., 325, 175 (2008)

Formule : C₁₈H₂₅N₃O₂

Couleur et forme : Neat

Masse moléculaire : 315.41

Ref: TR-S143480

(2R,2R,Trans)-saxagliptin

CAS : 1564266-03-0

(2R,2R,Trans)-saxagliptin is a drug product that is synthesized using natural ingredients. It is a custom synthesis and has high purity. The CAS number for this compound is 1564266-03-0. (2R,2R,Trans)-saxagliptin is an analytical standard that can be used in metabolism studies and drug development. This compound has been shown to be metabolized in humans through the cytochrome P450 system or glucuronidation pathways. Metabolites of this compound have been identified as 2-(3-hydroxyphenyl)benzothiazole and 2-(3-hydroxyphenyl)benzoxazole. Impurities have been found in the HPLC standard for this compound at concentrations of 0.0025%.

Formule : C₁₈H₂₅N₃O₂

Degré de pureté : Min. 95%

Masse moléculaire : 315.40 g/mol

Ref: 3D-PMC26603

(2’R,2R,Trans)-Saxagliptin

CAS : 1564266-03-0

Formule : C₁₈H₂₅N₃O₂

Masse moléculaire : 315.42

Ref: ST-EA-CP-S19042