CAS 1574321-31-5

EGFR-IN-139

CAS : 1574321-31-5

EGFR-IN-139 (compound PD 18) is an EGFR inhibitor with IC50 values of 12.88 nM (wild type), 10.84 nM (L858R/T790M), and 42.68 nM (L858R/T790M/C797S). It demonstrates significant anticancer activity against the A549 and H1975 cancer cell lines, which express high levels of EGFR. EGFR-IN-139 exhibits strong selectivity for cancer cells and can be utilized in research on non-small cell lung cancer (NSCLC).

Formule : C₂₇H₂₅ClN₂O₄

Couleur et forme : Solid

Masse moléculaire : 476.951

Ref: TM-T204772