CAS 15761-39-4
:BOC-L-Proline
Description :
BOC-L-Proline, avec le numéro CAS 15761-39-4, est un dérivé de l'acide aminé proline, caractérisé par la présence d'un groupe protecteur tert-butyloxycarbonyle (BOC). Ce composé est couramment utilisé dans la synthèse peptidique comme groupe protecteur pour le groupe amino de la proline, facilitant la formation de liaisons peptidiques sans réactions secondaires indésirables. BOC-L-Proline est typiquement un solide cristallin blanc à blanc cassé, et il est soluble dans des solvants organiques tels que le dichlorométhane et le diméthylformamide, mais moins soluble dans l'eau. Le groupe BOC est facilement éliminé dans des conditions acides, permettant la régénération du groupe amino libre pour d'autres réactions. Ce composé joue un rôle significatif dans la synthèse de divers peptides et produits pharmaceutiques, ce qui le rend précieux en chimie médicinale et en biochimie. Sa stabilité, sa facilité de manipulation et sa compatibilité avec diverses conditions de réaction contribuent à son utilisation répandue en chimie organique synthétique.
Formule :C10H17NO4
InChI :InChI=1/C10H17NO4/c1-10(2,3)15-9(14)11-6-4-5-7(11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)/p-1/t7-/m0/s1
Code InChI :InChIKey=ZQEBQGAAWMOMAI-ZETCQYMHSA-N
SMILES :C(OC(C)(C)C)(=O)N1[C@H](C(O)=O)CCC1
Synonymes :- (2S)-1,2-Pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester
- (2S)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylate
- (2S)-1-Boc-pyrrolidine-2-carboxylic acid
- (2S)-1-[(2-Methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
- (2S)-1-tert-Butoxycarbonylpyrrolidine-2-carboxylic acid
- (S)-1,2-Pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester
- (S)-1-(tert-Butoxycarbonyl)-2-pyrrolidinecarboxylic acid
- (S)-1-Boc-β-proline
- (S)-N-tert-Butoxycarbonylproline
- (S)-Pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
- 1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (2S)-
- 1,2-Pyrrolidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (S)-
- 1,2-Pyrrolidinedicarboxylic acid, 1-tert-butyl ester, <span class="text-smallcaps">L</span>-
- 1,2-Pyrrolidinedicarboxylic acid, 1-tert-butyl ester, L-
- 1-(Tert-Butoxycarbonyl)Proline
- 1-(tert-Butoxycarbonyl)-(2S)-pyrrolidine-2-carboxylic acid
- 1-(tert-Butoxycarbonyl)-(S)-proline
- 1-(tert-Butyl)hydrogen-(S)-pyrrolidin-1,2-dicarboxylat
- 1-(tert-butoxycarbonyl)-L-proline
- 1-(tert-butyl) hydrogen (S)-pyrrolidine-1,2-dicarboxylate
- 1-Boc-L-Proline
- 1-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-proline
- 1-tert-Butyl (S)-pyrrolidine-1,2-dicarboxylate
- 1-tert-Butyloxycarbonyl-<span class="text-smallcaps">L</span>-proline
- 1-tert-Butyloxycarbonyl-L-proline
- <span class="text-smallcaps">L</span>-N-Boc-proline
- BOC-<span class="text-smallcaps">L</span>-Proline
- Boc-<span class="text-smallcaps">L</span>-Pro
- Boc-L-Pro-OH
- Boc-Pro-OH
- Hydrogeno-(S)-pyrrolidine-1,2-dicarboxylate de 1-(tert-butyle)
- L-N-Boc-proline
- N-(t-Butoxycarbonyl)proline
- N-(tert-Butoxycarbonyl)-(S)-proline
- N-(tert-Butoxycarbonyl)-<span class="text-smallcaps">L</span>-proline
- N-(tert-Butoxycarbonyl)-L-proline
- N-(tert-Butoxycarbonyl)proline
- N-(tert-Butyloxycarbonyl)-<span class="text-smallcaps">L</span>-proline
- N-(tert-Butyloxycarbonyl)-L-proline
- N-Boc-(S)-proline
- N-Boc-<span class="text-smallcaps">L</span>-proline
- N-Boc-L-proline
- N-[(1,1-Dimethylethoxy)carbonyl]-(S)-proline
- N-alpha-tert-BOC-L-proline
- Nsc 164660
- hidrogeno-(S)-pirrolidina-1,2-dicarboxilato de 1-(terc-butilo)
- tert-Butoxycarbonyl-L-proline
- tert-Butyloxycarbonyl-L-proline
- trans-N-(tert-Butoxycarbonyl)-4-hydroxy-<span class="text-smallcaps">L</span>-proline
- BOC-L-PROLINE-OH
- N-ALPHA-T-BUTOXYCARBONYL-L-PROLINE
- BOC-L-PRO
- N-ALPHA-TERT-BUTYLOXYCARBONYL-L-PROLINE
- N-T-BOC-L-PROLINE
- BOC-L-PROLINE
- N-ALPHA-T-BOC-L-PROLINE
- BOC-PRO
- N-T-BUTOXYCARBONYL-L-PROLINE
- BOC-PYRD(2)-OH
- N-(TERT-BUTOXYCARBONYL)-L-PROILNE
- N-ALPHA-T-BUTOXYCARBONYL-L-PYRROLIDINE-2-CARBOXYLIC ACID
- Voir plus de synonymes
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13 produits concernés.
N-(tert-Butoxycarbonyl)-L-proline
CAS :Formule :C10H17NO4Degré de pureté :>99.0%(T)Couleur et forme :White to Almost white powder to crystalMasse moléculaire :215.25N-Boc-L-proline, 99%
CAS :N-Boc-L-proline is used as an intermediate in organic synthesis. It is also used to prepare daclatasvir, which inhibits the hepatitis C virus (HCV) non-structural 5A (NS5A) protein. Further, it is used as a drug in the treatment of hepatitis C virus (HCV). This Thermo Scientific Chemicals brand prod
Formule :C10H17NO4Degré de pureté :99%Couleur et forme :Crystals or powder or crystalline powder, WhiteMasse moléculaire :215.25Boc-Pro-OH
CAS :Bachem ID: 4000220.
Formule :C10H17NO4Degré de pureté :> 99%Couleur et forme :WhiteMasse moléculaire :215.25N-(tert-Butoxycarbonyl)-L-proline
CAS :Formule :C10H17NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :215.2463Ref: IN-DA003OI7
10g24,00€1kg118,00€25g24,00€50g24,00€5kg291,00€100g28,00€10kg530,00€250g49,00€500g70,00€(2S)-Pyrrolidine-2-carboxylic acid, N-BOC protected
CAS :(2S)-Pyrrolidine-2-carboxylic acid, N-BOC protectedFormule :C10H17NO4Degré de pureté :99%Couleur et forme : white solidMasse moléculaire :215.25g/molBoc-Pro-OH
CAS :M03314 - Boc-Pro-OH
Formule :C10H17NO4Degré de pureté :97%Couleur et forme :SolidMasse moléculaire :215.249N-Boc-L-proline
CAS :Produit contrôléApplications N-Boc-L-proline is a useful synthetic intermediate. It is used to synthesize Daclatasvir (D101500) which nhibits the HCV protein NS5A. Daclatasvir (D101500) can be used as a drug candidate for the treatment of hepatitis C (HCV).
References Gao, M., et al.: Nature, 465(7294), 96 (2010); Bell, T. W., Chem. Med. Chem., 5(10), 1663 (2010);Formule :C10H17NO4Couleur et forme :NeatMasse moléculaire :215.25BOC-L-Proline extrapure, 99%
CAS :Formule :C10H17NO4Degré de pureté :min. 99%Couleur et forme :White, Crystalline powderMasse moléculaire :215.30N-Boc-L-proline
CAS :N-Boc-L-proline is a proline derivative that has been synthesized as a drug candidate for cancer treatment. It has been shown to inhibit the activity of the enzyme, buserelin, which is involved in the synthesis of histamine and other substances. N-Boc-L-proline has also been shown to cause neuronal death by hydrogen bond formation with nitrogen nucleophiles in the brain, leading to apoptosis. The chromatographic method was used to analyze reaction products from N-Boc-L-proline with sodium carbonate. This compound has solubility data and an intramolecular hydrogen bond that can be detected by nmr spectroscopy. Trifluoroacetic acid was used as a solvent for this experiment.Formule :C10H17NO4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :215.25 g/molBoc-Pro-OH
CAS :Boc-Pro-OH is a synthetic amino acid that is used in the preparation of samples for gas chromatography. Boc-Pro-OH has antiinflammatory activity, and can be used to treat cancer. It is also used as an intermediate in the synthesis of amides, which are important in pharmaceuticals. Boc-Pro-OH is soluble in water and carbonate buffer solutions, but insoluble in ethanol. The chemical structure of this molecule is unusual because it contains a Boc group.
Formule :C10H17NO4Degré de pureté :Min. 95%Masse moléculaire :215.25 g/mol
