CAS 1603833-56-2

Amyloid-β-IN-3

CAS : 1603833-56-2

Amyloid-β-IN-3 (EX.113) is a selective inhibitor of γ-secretase. It demonstrates inhibitory activity on Aβ42 secretion in H4 cells, with an EC50 value of 148 nM. By modulating the catalytic activity of γ-secretase, Amyloid-β-IN-3 decreases Aβ42 production, thereby alleviating neurotoxicity caused by Aβ deposition. It holds potential for Alzheimer's disease (AD) research.

Formule : C₂₂H₂₁F₂N₃O₂

Couleur et forme : Solid

Masse moléculaire : 397.42

Ref: TM-T207233