CAS 163130-29-8

Toremifene N-Oxide Fumarate

CAS : 163130-29-8

Formule : C₂₆H₂₈ClNO₂·C₄H₄O₄

Couleur et forme : White To Off-White Solid

Masse moléculaire : 421.97 116.07

Ref: 4Z-T-418

Toremifene N-Oxide-d6

Produit contrôlé

CAS : 163130-29-8

Formule : C₂₆D₆H₂₂ClNO₂

Couleur et forme : Neat

Masse moléculaire : 427.996

Ref: TR-T547512

Toremifene-N-oxide

CAS : 163130-29-8

Toremifene-N-oxide is a drug that has been shown to have genotoxic effects in human liver cells in an incubated system. Toremifene-N-oxide is the active form of toremifene, which is a selective estrogen receptor modulator (SERM). Toremifene-N-oxide is metabolized by peroxidases and can react with reactive oxygen species (ROS) to produce DNA damage. It also binds to DNA at the site of supercoiled DNA, leading to changes in the molecule's structure. Toremifene-N-oxide has been shown to have an optimum pH of 7.4 and ionization mass of 367. This drug binds to lactoperoxidase found in human liver cells and produces reactive molecules that cause oxidative DNA damage.

Formule : C₂₆H₂₈ClNO₂

Degré de pureté : Min. 95%

Masse moléculaire : 421.96 g/mol

Ref: 3D-IT158042