CAS 1638646-27-1

VU0453379

CAS : 1638646-27-1

VU0453379 is a highly selective and central nervous system penetrant positive allosteric modulator of glucagon-like peptide-1R (EC50: 1.3 μM).

Formule : C₂₆H₃₄N₄O₂

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 434.57

Ref: TM-T17242

VU0453379

CAS : 1638646-27-1

VU0453379 is a chemical compound that functions as a positive allosteric modulator (PAM) of the M4 muscarinic acetylcholine receptor. It is synthetically derived through medicinal chemistry processes designed to selectively enhance receptor signaling pathways. VU0453379 acts by binding to an allosteric site on the M4 receptor, distinct from the orthosteric site where endogenous neurotransmitters bind. This binding potentiates receptor sensitivity and activity in response to acetylcholine, thereby amplifying receptor-mediated signaling pathways.

Formule : C₂₆H₃₄N₄O₂

Degré de pureté : Min. 95%

Masse moléculaire : 434.6 g/mol

Ref: 3D-NQC64627