CAS 1642300-52-4

KPT-8602

CAS : 1642300-52-4

Formule : C₁₇H₁₀F₆N₆O

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 428.2913

Ref: IN-DA00ABSL

Eltanexor

CAS : 1642300-52-4

Eltanexor

Degré de pureté : ≥98%

Masse moléculaire : 428.29g/mol

Ref: 54-BUP12899

Eltanexor

CAS : 1642300-52-4

Eltanexor, an oral XPO1 inhibitor, induces apoptosis in leukemia cells; EC50=60.9 nM.

Formule : C₁₇H₁₀F₆N₆O

Degré de pureté : 99.6% - ≥98%

Couleur et forme : Solid

Masse moléculaire : 428.29

Ref: TM-T11766L

Eltanexor(KPT-8602)

CAS : 1642300-52-4

Eltanexor is a small molecule that has been shown to have minimal toxicity and synergistic cell activity in vivo. It is a selective inhibitor of TLR9, which is an important part of the innate immune response. Eltanexor has been shown to inhibit the transcriptional regulation of squamous cell carcinoma cells and also inhibit cellular transformation in vitro. Eltanexor inhibits nuclear factor-κB (NF-κB) and activator protein 1 (AP-1) pathways by inhibiting the activation of JAK2 V617F. This inhibition leads to decreased inflammatory cytokines production and inflammation, which may lead to cancer prevention.

Formule : C₁₇H₁₀F₆N₆O

Degré de pureté : Min. 95%

Masse moléculaire : 428.29 g/mol

Ref: 3D-SQC30052