CAS 1658520-97-8

Trimetrexate trihydrochloride

CAS : 1658520-97-8

Trimetrexate is a cytotoxic drug used to treat cancer and inflammatory bowel disease. It is an antimetabolite that inhibits the synthesis of DNA by competing with thymidine triphosphates for incorporation into DNA. Trimetrexate has been shown to have synergistic effects with other drugs, such as antibiotics, chemotherapeutic agents, or immunosuppressants, when administered together. This drug has minimal toxicity and low side-effects. Trimetrexate also targets intracellular targets and has been shown to be effective against metastatic colorectal cancer without affecting healthy cells in the gastrointestinal tract.

Formule : C₁₉H₂₆Cl₃N₅O₃

Degré de pureté : Min. 95%

Masse moléculaire : 478.8 g/mol

Ref: 3D-IRC52097

CI-898 HCl

CAS : 1658520-97-8

CI-898 HCl: lipophilic antifolate, DHFR inhibitor, effective on methotrexate-resistant cancers, synergizes with other drugs in advanced P338 leukemia.

Formule : C₁₉H₂₆Cl₃N₅O₃

Couleur et forme : Solid

Masse moléculaire : 478.8

Ref: TM-T70304