CAS 166196-54-9

Pyridine, 4-(4-bromo-1H-pyrazol-3-yl)-

CAS : 166196-54-9

Formule : C₈H₆BrN₃

Degré de pureté : 95%

Couleur et forme : Solid

Masse moléculaire : 224.0573

Ref: IN-DA001WKM

4-(4-Bromo-1H-pyrazol-3-yl)pyridine

CAS : 166196-54-9

4-(4-Bromo-1H-pyrazol-3-yl)pyridine

Degré de pureté : 95%

Masse moléculaire : 224.061g/mol

Ref: 54-OR74694

HDGFRP2/PSIP1-IN-1

CAS : 166196-54-9

Compound BPP (HDGFRP2/PSIP1-IN-1) is a dual inhibitor targeting the PWWP domains of Hepatoma-derived Growth Factor Related Protein 2 (HDGFRP2) and its homologue PSIP1. This compound effectively hinders the occurrence and progression of Diffuse Intrinsic Pontine Glioma (DIPG). It demonstrates binding affinity with a Kd value of 7 μM for HDGFRP2, indicative of its efficient ligand efficacy at 0.47. Additionally, Compound BPP exhibits a Kd value of 27 μM when binding to the PSIP1 PWWP domain, and a Kd value of 14 μM against HDGFRP3, confirming its potency as an inhibitor within the HDGFRP2 PWWP subfamily.

Formule : C₈H₆BrN₃

Couleur et forme : Solid

Masse moléculaire : 224.06

Ref: TM-T200639

4-(4-Bromo-1H-pyrazol-3-yl)pyridine

CAS : 166196-54-9

Formule : C₈H₆BrN₃

Degré de pureté : 95%

Couleur et forme : Solid

Masse moléculaire : 224.061

Ref: 10-F306631