CAS 1665195-94-7

BAZ2-ICR

CAS : 1665195-94-7

Formule : C₂₀H₁₉N₇

Masse moléculaire : 357.42

Ref: 4Z-B-147001

BAZ2-ICR

CAS : 1665195-94-7

BAZ2-ICR is a novel atypical anti-inflammatory cytokine that belongs to the TGF-β superfamily. It is a drug target for protozoan parasites and cancer cells. BAZ2-ICR is an acetylated molecule that has been shown to be biologically active in vitro using cell culture and functional studies. It also has anti-cancer properties against cell lines derived from breast, colon, prostate, lung, and brain cancers. BAZ2-ICR also reduces intestinal inflammation by inhibiting NFκB activation and IL8 production in a mouse model of colitis.

Formule : C₂₀H₁₉N₇

Degré de pureté : Min. 95%

Masse moléculaire : 357.41 g/mol

Ref: 3D-QRC19594

BAZ2-ICR

CAS : 1665195-94-7

BAZ2-ICR is an epigenetic chemical probe and it also is a potent, selective, cell active and orally active BAZ2A/B bromodomains inhibitor with IC50s of 130 nM and 180 nM, and Kds of 109 nM and 170 nM, respectively. BAZ2-ICR shows 10-15-fold selectivity for binding BAZ2A/B over CECR2 and >100-fold selectivity over all other bromodomains.

Formule : C₂₀H₁₉N₇

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 357.41

Ref: TM-T14512