CAS 1780303-76-5

DDR1-IN-1 dihydrochloride

CAS : 1780303-76-5

DDR1-IN-1 dihydrochloride: potent DDR1 kinase inhibitor; IC50=105 nM; 4x less effective on DDR2 (IC50=413 nM).

Formule : C₃₀H₃₃Cl₂F₃N₄O₃

Couleur et forme : Solid

Masse moléculaire : 625.51

Ref: TM-T70202

DDR1-IN-1 dihydrochloride

CAS : 1780303-76-5

DDR1-IN-1 is a drug that belongs to the class of protein kinase inhibitors. It has been shown to inhibit the activity of n-cadherin, IGF-IR and insulin-like growth factor (IGF)-I. DDR1-IN-1 also inhibits the synthesis of collagen and cancer cell proliferation. The structure of DDR1-IN-1 is similar to discoidin, which may be responsible for its interactions with markers expressed on cells and autocrine effects. DDR1-IN-1 has been shown to inhibit the activity of kinases such as PKA, EGFR, PI3K/AKT, JAK2, CDK4/CDK6, SRC, FAK and PDGFR.

Formule : C₃₀H₃₃Cl₂F₃N₄O₃

Degré de pureté : Min. 95%

Masse moléculaire : 625.5 g/mol

Ref: 3D-FWC30376