CAS 1801787-56-3

3-Pyridinecarboxamide, 1,6-dihydro-N-[4-(4-methyl-1-piperazinyl)-3'-(4-morpholinylmethyl)[1,1'-biphenyl]-3-yl]-6-oxo-4-(trifluoromethyl)-

CAS : 1801787-56-3

Formule : C₂₉H₃₂F₃N₅O₃

Degré de pureté : 99%

Couleur et forme : Solid

Masse moléculaire : 555.5913

Ref: IN-DA0021QY

OICR-9429

CAS : 1801787-56-3

OICR-9429

Degré de pureté : ≥95%

Masse moléculaire : 555.59g/mol

Ref: 54-BUP03024

6-Oxo-4-Trifluoromethyl-1,6-Dihydro-Pyridine-3-Carboxylic Acid [4-(4-Methyl-Piperazin-1-Yl)-3'-Morpholin-4-Ylmethyl-Biphenyl-3-Yl]-Amide

CAS : 1801787-56-3

6-Oxo-4-Trifluoromethyl-1,6-Dihydro-Pyridine-3-Carboxylic Acid [4-(4-Methyl-Piperazin-1-Yl)-3'-Morpholin-4-Ylmethyl-Biphenyl-3-Yl]-Amide

Degré de pureté : 99%

Masse moléculaire : 555.59g/mol

Ref: 54-PC108771

OICR-9429

CAS : 1801787-56-3

OICR-9429 blocks WDR5 binding to MLL/Histone 3, hindering acute myeloid leukemia cell growth in vitro.

Formule : C₂₉H₃₂F₃N₅O₃

Degré de pureté : 97.07% - 99.93%

Couleur et forme : Solid

Masse moléculaire : 555.59

Ref: TM-T6916

OICR 9429

CAS : 1801787-56-3

A highly selective WD repeat-containing protein 5 (Wdr5) antagonist and modulator of histone lysine methylation. The compound competitively disrupts the interaction between the Wdr5 and Wdr5-INteracting region (WIN) of methyltransferases. It inhibits the cell proliferation and restores differentiation in p30-dependent acute myeloid leukemia models.

Formule : C₂₉H₃₂F₃N₅O₃

Degré de pureté : Min. 95%

Masse moléculaire : 555.59 g/mol

Ref: 3D-BO163662